Results 11 to 20 of about 556,071 (288)
International Journal of COPD, 2012 Background: Long-acting bronchodilators are central in the pharmacological management of patients with chronic obstructive pulmonary disease (COPD). The aim of this systematic review is to provide an overview of the studies evaluating the safety and ...
Ulrik CS
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The effect of the muscarinic antagonist scopolamine on regional cerebral blood flow during the performance of a memory task [PDF]
Experimental Brain Research, 1995 Paul M. Grasby +5 more
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Muscarinic Cholinergic Receptor Agonist and Peripheral Antagonist for Schizophrenia.
New England Journal of Medicine, 2021 BACKGROUND The muscarinic receptor agonist xanomeline has antipsychotic properties and is devoid of dopamine receptor-blocking activity but causes cholinergic adverse events.
S. Brannan +5 more
semanticscholar +1 more source
Practical considerations when prescribing a long-acting muscarinic antagonist for patients with COPD. [PDF]
Int J Chron Obstruct Pulmon Dis, 2018 D'Urzo AD, Kardos P, Wiseman R.
europepmc +3 more sources
Investigating the Unbinding of Muscarinic Antagonists from the Muscarinic 3 Receptor
Journal of Chemical Theory and Computation, 2023 Patient symptom relief is often heavily influenced by the residence time of the inhibitor-target complex. For the human muscarinic receptor 3 (hMR3), tiotropium is a long-acting bronchodilator used in conditions such as asthma or chronic obstructive pulmonary disease (COPD). The mechanistic insights into this inhibitor remain unclear; specifically, the
Buigues, Pedro J. +7 more
openaire +3 more sources
Cells, 2022 Irritable bowel syndrome (IBS) is a chronic functional bowel disorder characterized by intestinal dysmotility. Changes in intestinal microbiota (dysbiosis) can lead to alterations in neuro-muscular functions in the gut. Toll-like receptors (TLRs) 2 and 4
Elena Layunta +2 more
doaj +1 more source
Additive interaction of intrathecal ginsenosides and neostigmine in the rat formalin test [PDF]
Korean Journal of Anesthesiology, 2013 BackgroundThe authors evaluated the effect of intrathecal mixture of ginsenosides with neostigmine on formalin-induced nociception and made further clear the role of the spinal muscarinic (M) receptors on the activity of ginsenosides.MethodsA catheter ...
Cheon-Hee Park +3 more
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Functional effects of KCNQ K+ channels in airway smooth muscle
Frontiers in Physiology, 2013 KCNQ (Kv7) channels underlie a voltage-gated K+ current best known for control of neuronal excitability, and its inhibition by Gq/11-coupled, muscarinic signaling. Studies have indicated expression of KCNQ channels in airway smooth muscle (ASM), a tissue
Alexey I Evseev +7 more
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Effects of muscarinic and nicotinic receptors on contextual modulation in macaque area V1
Scientific Reports, 2021 Context affects the salience and visibility of image elements in visual scenes. Collinear flankers can enhance or decrease the perceptual and neuronal sensitivity to flanked stimuli. These effects are mediated through lateral interactions between neurons
Jose L. Herrero, Alexander Thiele
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Journal of Pharmacological Sciences, 2016 The present study investigated pharmacological characterizations of muscarinic acetylcholine receptor (AChR) subtypes involving ACh-induced endothelium-independent vasodilatation in rat mesenteric arteries.
Panot Tangsucharit +6 more
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