Results 61 to 70 of about 149,769 (206)
Epilepsia, EarlyView.Abstract Theta oscillations (4–12 Hz) are a prominent network rhythm within hippocampal and parahippocampal structures. Driven by cholinergic and γ‐aminobutyric acidergic inputs originating from the medial septum, physiological theta gates network excitability to control spatial navigation, memory encoding, and sensorimotor integration during specific ...
Maxime Lévesque, Massimo Avoli
wiley +1 more source
A new class of irreversible muscarinic antagonists: β-haloethylamine furoates
, 1976 The synthesis of a new class of ultra-long acting muscarinic antagonists is described. Furthermore, it is noted that the stability of the, in situ, aziridinium ion is sufficiently great so that these agents can be used to study the effect of temperature ...
Gerald M Rosen, Elmer J Rauckman
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Status epilepticus: Updates on mechanisms and treatments
Epilepsia Open, EarlyView.Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley +1 more source
Oscillometric assessment of bronchodilator response in horses with severe asthma during remission
Equine Veterinary Journal, EarlyView.Abstract Background During clinical remission of severe equine asthma (SEA), affected animals can be challenging to distinguish from healthy horses. In humans, the degree of bronchodilation achieved with a β2‐adrenergic bronchodilator is helpful in differentiating asthmatics from healthy subjects.
Séléna de Wasseige +2 more
wiley +1 more source
Novel muscarinic antagonists designed on the 1,4-dioxane scaffold
, 2010 The five subtypes of muscarinic receptors (M1-M5) are widely distributed on multiple organs and tissues and are critical to the maintenance of central and peripheral cholinergic neurotrasmission.
PIERGENTILI, Alessandro +7 more
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Journal of Magnetic Resonance Imaging, EarlyView.ABSTRACT Background Long‐acting muscarinic antagonists/long‐acting beta adrenoreceptor agonists lead to lung deflation and improved microvascular perfusion in hyperinflated chronic obstructive pulmonary disease (COPD), but with an unclear time course. Purpose To investigate the effect of inhalation of tiotropium/olodaterol (TIO/OLO) on MRI measures of ...
Agilo L. Kern +7 more
wiley +1 more source
Guidelines for the Treatment of Urinary Incontineence and Overactive Bladder
South African Family Practice, 2002 Urinary incontinence (UI) is the involuntary leakage of urine, while overactive bladder (OAB) is characterised by frequency, nocturia and urgency, with or without incontinence.
C.F. Heyns, G.W. Rienhardt
doaj +1 more source
Case report : Acute unintentional carbachol intoxication [PDF]
, 2006 Introduction: Intoxications with carbachol, a muscarinic cholinergic receptor agonist are rare. We report an interesting case investigating a (near) fatal poisoning.
Schulz, Martin +5 more
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The effects of royal jelly on human health: A narrative review of clinical studies
JSFA reports, EarlyView.Abstract Royal jelly (RJ) is a natural bioactive substance with documented effects on human health. This narrative review synthesizes evidence from clinical and clinically relevant experimental studies evaluating the therapeutic potential of RJ.
Georgios Goras +2 more
wiley +1 more source
Neurourology and Urodynamics, EarlyView.ABSTRACT Introduction Antimuscarinics, as the current first‐line pharmacologic therapies for overactive bladder, exhibit low patient adherence and high rates of reported side effects. As a modern alternative pharmaceutical treatment, beta‐3 agonists, which relax the urinary bladder, may be more tolerable for patients, increasing adherence and ...
Felicity Smith +2 more
wiley +1 more source