Results 121 to 130 of about 8,830 (256)

Acetylcholine release in mouse hippocampal CA1 preferentially activates inhibitory-selective interneurons via α4β2* nicotinic receptor activation [PDF]

, 2015
Acetylcholine (ACh) release onto nicotinic receptors directly activates subsets of inhibitory interneurons in hippocampal CA1. However, the specific interneurons activated and their effect on the hippocampal network is not completely understood ...
Bell, Karen A., Bell, L. Andrew, McQuiston, A. Rory   +2 more
core   +3 more sources

TAK-071, a muscarinic M1 receptor positive allosteric modulator, attenuates scopolamine-induced quantitative electroencephalogram power spectral changes in cynomolgus monkeys.

PLoS ONE, 2019
Activation of the muscarinic M1 receptor is a promising approach to improve cognitive deficits associated with cholinergic dysfunction in Alzheimer's disease, dementia with Lewy bodies, and schizophrenia.
Emi Kurimoto, Masato Nakashima, Haruhide Kimura, Motohisa Suzuki   +3 more
doaj   +1 more source

Acetylcholine induces fibrogenic effects via M2/M3 ACh receptors in NASH and in primary human hepatic stellate cells [PDF]

, 2016
BACKGROUND: The parasympathetic nervous system (PNS), via neurotransmitter Acetylcholine (ACh), modulates fibrogenesis in animal models. However, the role of ACh in human hepatic fibrogenesis is unclear.
Cordero, P, McKee, C, Morgan, ML, Mouraliderane, A, Nguyen, V, Oben, JA, Sigala, B, Soeda, J, Vinciguerra, M   +8 more
core  

Regulation of m4 muscarinic receptor gene expression [PDF]

Life Sciences, 1993
I.C. Wood, N.J. Buckley, D.A. Brown
openaire   +1 more source

MP11-07 ACTIVATION OF PRE-JUNCTIONAL MUSCARINIC M4 RECEPTOR FOR ENHANCING BLADDER CONTRACTILITY: IMPLICATIONS FOR UNDERACTIVE BLADDER (UAB) [PDF]

, 2019
Pradeep Tyagi, Naoki Yoshimura
openalex   +1 more source

Erratum: Investigation of M1/M4 Muscarinic Receptors in the Anterior Cingulate Cortex in Schizophrenia, Bipolar Disorder, and Major Depression Disorder [PDF]

, 2006
Katerina Zavitsanou, Andrew Katsifis, Filomena Mattner, Xu‐Feng Huang   +3 more
openalex   +1 more source

A sex-specific effect of M4 muscarinic cholinergic autoreceptor deletion on locomotor stimulation by cocaine and scopolamine

Frontiers in Molecular Neuroscience
ObjectiveAcetylcholine modulates the activity of the direct and indirect pathways within the striatum through interaction with muscarinic M4 and M1 receptors.
Anna Berezovskaia, Anna Berezovskaia, Morgan Thomsen, Morgan Thomsen, Morgan Thomsen, Anders Fink-Jensen, Anders Fink-Jensen, Anders Fink-Jensen, Gitta Wörtwein, Gitta Wörtwein, Gitta Wörtwein   +10 more
doaj   +1 more source

中枢神経系疾患治療薬の創製に向けた評価系の構築と行動薬理学的研究 [PDF]

, 2015
関西大
Nakako Tomokazu, 仲子 友和
core   +1 more source

Antipsychotic Drug-Like Effects of the Selective M4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator VU0152100 [PDF]

, 2014
Nellie Byun, Michael Grannan, Michael Bubser, Robert Barry, Analisa D. Thompson, John Rosanelli, Raajaram Gowrishankar, Nathaniel D. Kelm, Stephen Damon, Thomas M. Bridges, Bruce J. Melancon, James C. Tarr, John T. Brogan, Malcolm J. Avison, Ariel Y. Deutch, Jürgen Wess, Michael R. Wood, Craig W. Lindsley, John C. Gore, P. Jeffrey Conn, Carrie K. Jones   +20 more
openalex   +1 more source

Acetylcholine regulates the melanogenesis of retinal pigment epithelia cells via a cAMP-dependent pathway: A non-neuronal function of cholinergic system in retina

Heliyon
The turnover rate of melanogenesis in retinal pigment epithelium (RPE) and its molecular signaling remain unclear. This study aimed to investigate the role of cholinergic signaling in the process of melanogenesis of cultured RPE cells.
Ivan Kong, Gary Ka-Wing Yuen, Qi-Yun Wu, Maggie Sui-Sui Guo, Jin Gao, Tina Ting-Xia Dong, Karl Wah-Keung Tsim   +6 more
doaj   +1 more source