Results 191 to 200 of about 56,565 (298)

G Protein‐Coupled Receptor Signaling: Implications and Therapeutic Development Advances in Cancers

MedComm, Volume 6, Issue 10, October 2025.
G protein‐coupled receptors (GPCRs) are the dynamic protein family in the human genome. GPCR dysregulation aids in the advancement of cancer through increased migration, survival, and proliferation. Novel treatments that target GPCR signaling include orthosteric ligands, biased receptor mutants, PROTACs, and antibody–drug conjugates.
Inamu Rashid Khan, Sana Khurshid, Saud Almawash, Rakesh Kumar, Ammira S. Al‐Shabeeb Akil, Ajaz A. Bhat, Muzafar A. Macha   +6 more
wiley   +1 more source

Herbal Amara extract induces gastric fundus relaxation via inhibition of the M2 muscarinic receptor. [PDF]

Neurogastroenterol Motil
Piqué-Borràs MR, Röhrl J, Künstle G.
europepmc   +1 more source

Neuronal localization of m1 muscarinic receptor immunoreactivity in the monkey basolateral amygdala. [PDF]

J Comp Neurol, 2021
McDonald AJ, Mott DD.
europepmc   +1 more source

Neuronal muscarinic receptors attenuate vagally-induced contraction of feline bronchial smooth muscle [PDF]

, 1985
L.C. Blaber, A.D. Fryer, Jennifer Maclagan   +2 more
openalex   +1 more source

A Comparison of the Molecular Pharmacological Properties of Current Short, Long, and Ultra‐Long‐Acting β2‐Agonists Used for Asthma and COPD

Pharmacology Research &Perspectives, Volume 13, Issue 5, October 2025.
ABSTRACT β‐agonists have been used in asthma for 120 years. There are two recent changes: ultra‐long‐acting agonists for COPD and new asthma guidelines recommending formoterol/ICS inhalers phasing out short‐acting salbutamol inhalers. Few studies directly compare the molecular pharmacological properties of short (salbutamol, terbutaline, fenoterol ...
Richard G. W. Proudman, Jillian G. Baker
wiley   +1 more source

Overcoming Obstacles to Targeting Muscarinic Receptor Signaling in Colorectal Cancer. [PDF]

Int J Mol Sci, 2021
Ali O, Tolaymat M, Hu S, Xie G, Raufman JP.   +4 more
europepmc   +1 more source

Batrachotoxin changes the properties of the muscarinic receptor in rat brain and heart: possible interaction(s) between muscarinic receptors and sodium channels.

, 1985
Malka Cohen‐Armon, Yoel Kloog, Yoav I. Henis, Mordechai Sokolovsky   +3 more
openalex   +1 more source

Intracellular calcium release mediated by two muscarinic receptor subtypes [PDF]

, 1988
Erwin Neher, Alain Marty, Kazuhiko Fukuda, Tai Kubo, Shosaku Numa   +4 more
openalex   +1 more source

Correction to: From theory to therapy: unlocking the potential of muscarinic receptor activation in schizophrenia with the dual M1/M4 muscarinic receptor agonist xanomeline and trospium chloride and insights from clinical trials. [PDF]

Int J Neuropsychopharmacol
europepmc   +1 more source

Reactivation-dependent transfer of fear memory between contexts requires M1 muscarinic receptor stimulation in dorsal hippocampus of male rats. [PDF]

Learn Mem
Abouelnaga KH, Huff AE, Jardine KH, O'Neill OS, Winters BD.   +4 more
europepmc   +1 more source