Results 141 to 150 of about 29,348 (182)

Muscarinic Receptor Subtypes: Implications for Therapy

1993
At least three subtypes of muscarinic receptor have been localised to human airways. M1-receptors facilitate ganglionic transmission and therefore enhance cholinergic reflexes, M2-receptors are localised to post-ganglionic cholinergic nerve terminals and inhibit the release of acetylcholine and M3-receptors on airway smooth muscle mediate constriction ...
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Muscarinic receptor subtypes: Modulation of ion channels

Life Sciences, 1993
The discovery of five muscarinic receptor subtypes by molecular genetic techniques has resulted in new approaches to understanding their function. This involves the expression of the individual genes encoding each receptor subtype in isolation, such that their effects and mechanisms of action can be studied.
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Subtypes of Muscarinic Cholinergic Receptors

1989
Acetylcholine released from neurons has effects on many biological processes. These effects are mediated through two major classes of receptors termed nicotinic and muscarinic cholinergic receptors. There is currently strong evidence supporting the concept that both of these major classes of cholinergic receptors are themselves comprised of distinct ...
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Muscarinic agonist receptor subtypes in aging rat brain

Neurobiology of Aging, 1982
Whole brain homogenates from rats aged 6 months (young) and 24 months (old) showed a decline with age of the pre-synaptic cholinergic marker, choline acetyltransferase, and also of total specific binding sites for the muscarinic antagonist L(-)quinuclidinyl benzilate (L-QNB).
Briggs, Roger S., Petersen, Meryl M., Cook, Peter J.   +2 more
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Subtypes of muscarinic receptors regulating gallbladder cholinergic contractions

Gastroenterology, 1998
The aim of this study was to determine the functional role of muscarinic receptor subtypes regulating gallbladder cholinergic contractions. Electrical field stimulation (EFS; 16 Hz) produced contractile responses of guinea pig gallbladder muscle strips in vitro that were inhibited by 1 μM tetrodotoxin (2 ± 2% of control) and 1 μM atropine (1 ± 1% of ...
H P, Parkman, A P, Pagano, J P, Ryan
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Muscarinic Receptor Subtypes

New England Journal of Medicine, 1989
Jeffrey S. Flier, Lisa H. Underhill, Raj K. Goyal   +2 more
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Muscarinic Receptor Subtypes in Smooth Muscle

2020
Muscarinic Receptor Classification, M. Caulfield Muscarinic Acetylcholine Receptor Signaling Pathways in Smooth Muscle, R.A.J. Challiss and J.L. Blank Muscarinic Receptors and Gastrointestinal Smooth Muscle, F.J. Ehlert, E.A. Thomas, E.H. Gerstin, and M.T. Griffin Muscarinic Receptors and Genitourinary Smooth Muscle, R.M. Eglen and S.S.
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Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Chimeric antigen receptor T‐cell therapy in multiple myeloma: A comprehensive review of current data and implications for clinical practice

Ca-A Cancer Journal for Clinicians, 2023

exaly  

Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-Vornhagen, Boris Böll, Victoria Metaxa   +2 more
exaly