Results 181 to 190 of about 425,571 (245)

Muscle Fat Infiltration in Patients with Multiple Myeloma: A Case-Control Study. [PDF]

Int J Gen Med
Zhu T, Zhou H, Zhang D, Chen X, Lu X.
europepmc   +1 more source

Multiscale Cell–Cell Interactive Spatial Transcriptomics Analysis

Advanced Science, EarlyView.
In this study, we present the MultiScale Cell‐Cell Interactive Spatial Transcriptomics Analysis method, which unites the strengths of spatially resolved deep learning techniques with a topological representation of multi‐scale cell‐cell similarity relations.
Sean Cottrell, Guo‐Wei Wei
wiley   +1 more source

The role of exercise-induced short-chain fatty acids in the gut-muscle axis: implications for sarcopenia prevention and therapy. [PDF]

Front Microbiol
Fang J, Yan W, Sun X, Chen J.
europepmc   +1 more source

Acetylation of the Mitochondrial Chaperone GRP75 Governs ER‐Mitochondrial Calcium Homeostasis and Hepatocyte Insulin Resistance

Advanced Science, EarlyView.
Overnutrition exacerbates insulin resistance (IR) and is linked to excessive mitochondrial protein acetylation. However, it remains unclear whether and how mitochondrial protein acetylation influences IR. GCN5L1‐dependent downregulation of GRP75 acetylation at K567/612 consequently enhances ER‐mitochondrial calcium flux and induces ER stress.
Danni Wang, Jiaqi Zhang, Xinyu Yang, Qiqi Zhang, Xiuya Hu, Xin Lu, Hanni Li, Xue Bai, Kai Zhang, Michael N. Sack, Yongsheng Chang, Yingmei Wang, Lingdi Wang, Lu Zhu   +13 more
wiley   +1 more source

Skeletal muscle alterations in type 2 diabetes mellitus with and without dyslipidemia. [PDF]

Lipids Health Dis
Yigit S, Eksi BU, Satman I, Dayican DK, Calikoglu F, Sahin HR, Perone F, Akinci B.   +7 more
europepmc   +1 more source

Single‐Cell Immune Profiling Reveals Neutrophils Promote Myasthenia Gravis Exacerbation Through BAFF Secretion

Advanced Science, EarlyView.
Single‐cell transcriptomics and clinical data show that during myasthenia gravis (MG) exacerbation, bone marrow mature neutrophils expand and enter blood, with parallel increase of B‐cell activating factor (BAFF)–positive neutrophils. Experimental autoimmune myasthenia gravis (EAMG) confirms a pathogenic interferon‐γ (IFN‐γ)–neutrophil–BAFF axis ...
Zhaoxu Zhang, Jingya Dong, Mengyuan Qiu, Jie Bai, Xufeng Cheng, Xiaodong Song   +5 more
wiley   +1 more source

Exercise, Epigenetics, and Body Composition: Molecular Connections. [PDF]

Cells
Williams A, Wadsworth DD, Geetha T.
europepmc   +1 more source

Centimeter‐Scale Self‐Assembling Tendon Organoids Drive Tissue Regeneration

Advanced Science, EarlyView.
Centimeter‐scale tendon organoids are engineered by mimicking the extracellular matrix and optimizing chemical cues to guide tendon stem/progenitor cells. These large, self‐assembling constructs overcome conventional size limitations and exhibit enhanced tenogenic differentiation, extracellular matrix production, and mechanical resilience. Their tissue‐
Tianshun Fang, Hong Zhang, Yuanhao Xie, Xiongfeng Li, Xi Liu, Zichen Wang, Yiwen Xue, Xiaohui Xia, Zetao Wang, Tingyun Lei, Ruifu Lin, Weiliang Shen, Bingbing Wu, Yishan Chen, Yanan Du, Xiao Chen, Zi Yin   +16 more
wiley   +1 more source

Myo-MOVES: a custom electrical stimulation system for functional studies of 3D bioengineered muscle.

Lab Chip
Ruiz-Gutiérrez M, Tejedera-Villafranca A, Pujol-Pinto S, Ramón-Azcón J, Fernández-Costa JM.   +4 more
europepmc   +1 more source

Novel fat infiltration combined with muscle parameters for predicting postoperative complications following total knee arthroplasty: a retrospective study. [PDF]

BMC Musculoskelet Disord
Chen J, Zhang S, Ma C, Fu Z.
europepmc   +1 more source