Results 181 to 190 of about 2,132,550 (292)

Comprehensive Review of Sepsis-Related Skeletal Muscle Atrophy: Mechanisms, Diagnosis and Therapeutic Strategies. [PDF]

J Inflamm Res
Wu Q, Huang Q, Xu Z, Hou C, Wang C.
europepmc   +1 more source

NAD+‐Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell Functions Through NAD+ Synthesis Pathway in Colorectal Cancer

Advanced Science, EarlyView.
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu, Yingjie Dong, Jianghui Tong, Jingxuan Xia, Longhao Zhao, Zi Geng, Yingxin Lin, Jinghe Zhang, Xinyi Liu, Manqi Fang, Xi Jin, Yujing Bi, Guangwei Liu   +12 more
wiley   +1 more source

Longitudinal assessment of lower limb muscle quantity and quality in acute stroke patients. [PDF]

J Rehabil Med
Yamauchi W, Akima H.
europepmc   +1 more source

PTG‐Dependent Glycogen Metabolic Dysfunction Drives Impaired Adipose Browning: A Novel Mechanism Linking PM2.5 to Metabolic Disorders

Advanced Science, EarlyView.
This study provides the first evidence that PM2.5 impairs iWAT browning via PTG‐mediated glycogen metabolism disruption, which is initiated by ADRB3 inhibition and subsequently triggers VEGFB upregulation. It thereby delineates the ADRB3‐PTG‐VEGFB axis as central to PM2.5‐induced metabolic dysfunction and identifies adipose glycogen metabolism as a ...
Limin Wang, Renjie Hu, Yanxi Chai, Ping He, Sanduo Li, Lisha Zhao, Wenbin Zhao, Lu Zhang, Li Qin, Ran Li, Xiaoli Hou, Qinghua Sun, Cuiqing Liu   +12 more
wiley   +1 more source

An Integrated Multi-Omics Study of Mammalian Skeletal, Cardiac, and Smooth Muscles. [PDF]

Int J Mol Sci
Tang S, Wang K, Li D, Ma Y, Peng L, Liao S, Ma H, Wei H.   +7 more
europepmc   +1 more source

A quantitative analysis of 3D-cell distribution in regenerating muscle-skeletal system with synchrotron X-ray computed microtomography. [PDF]

Sci Rep, 2018
Tesařová M, Mancini L, Simon A, Adameyko I, Kaucká M, Elewa A, Lanzafame G, Zhang Y, Kalasová D, Szarowská B, Zikmund T, Novotná M, Kaiser J.   +12 more
europepmc   +1 more source

Targeting Endothelial KDM5A to Attenuate Aging and Ameliorate Age‐Associated Metabolic Abnormalities

Advanced Science, EarlyView.
This study identifies endothelial KDM5A as a key regulator of aging. KDM5A deficiency accelerates aging by enhancing H3K4me3‐mediated FABP4 expression, disrupting fatty acid metabolism, and promoting multi‐organ senescence. KDM5A restoration or FABP4 inhibition reverses these adverse effects and extends lifespan, positioning the KDM5A/FABP4 axis as a ...
Rifeng Gao, Lifeng Liang, Ling Yang, Chunyu Lyu, Yang Lyu, Weijun Yang, Jiaran Shi, Wei Wei, Jiahui Cheng, Xiaolei Sun, Xian Zhu, Chao Chen, Xiaoting Xu, Jianchuang Qi, Wenli Li, Yizhe Zhang, Xiao Zhang, Yan Zhou, Aiqiang Dong, Juntao Chen, Bo Li, Kun Yang   +21 more
wiley   +1 more source

Changes in Components of Sarcopenia Diagnostic Criteria Throughout the Surgical Treatment of Oesophagogastric Cancer Surgery: A Prospective Longitudinal Study. [PDF]

J Hum Nutr Diet
Murnane LC, Forsyth AK, Koukounaras J, Shaw K, Paul E, Brown WA, Tierney AC, Burton PR.   +7 more
europepmc   +1 more source

Biohybrid Tendons Enhance the Power‐to‐Weight Ratio and Modularity of Muscle‐Powered Robots

Advanced Science, EarlyView.
Biohybrid robots powered by skeletal muscle actuators are capable of dynamically adapting to environmental cues. This study takes inspiration from native muscle–tendon architecture by leveraging tough hydrogels as synthetic tendons for muscle actuators to enhance the power‐to‐weight ratio and modularity of biohybrid machines.
Nicolas Castro, Ronald Heisser, Maheera Bawa, Bastien Aymon, Sarah Wu, Annika Marschner, Sonika Kohli, Angel Bu, Laura Rosado, Martin Culpepper, Xuanhe Zhao, Ritu Raman   +11 more
wiley   +1 more source

Enhanced Expression of IL32 mRNA in Skeletal Muscles in the Context of Head and Neck Carcinomas. [PDF]

J Cachexia Sarcopenia Muscle
Baïche I, Hachicha H, Ragot T, Gracia C, Gelin A, Gader A, Even C, Breuskin I, Casiraghi O, Dayris T, Dall'Ollio F, Brenner C, Benihoud K, Vassetzky Y, Bidault F, Gorphe P, Busson P, Chen F.   +17 more
europepmc   +1 more source