Results 201 to 210 of about 461,055 (267)

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

Advanced Science, EarlyView.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su, Ye Tian, Fan Zhao, Jing Li, Suryaji Patil, Chunyu Zhu, Yujia Tian, Junrong Wang, Jiating Liu, Aoqi Xiang, Hua Guan, Lusha Zhang, Xiaochang Chen, Airong Qian, Qi Yu   +14 more
wiley   +1 more source

Aging-Related Muscle Bmal1 Decline Contributes to Bone Loss in Mice via Enhancing IL-1α-Mediated Osteoclastogenesis. [PDF]

Aging Cell
Huang K, Qian J, Wang Y, Zhang F, Xu Y, Zhai Q.   +5 more
europepmc   +1 more source

Heme Metabolism-Derived Carbon Monoxide Regulates Skeletal Muscle Function. [PDF]

J Cachexia Sarcopenia Muscle
Alves de Souza RW, In Kim H, Alves PKN, da Paixão AO, Rasmussen A, Shankar S, Harbison J, Voltarelli VA, Otterbein LE.   +8 more
europepmc   +1 more source

Skeletal muscle dysfunction in COPD: miRNAs, myokines and exercise. [PDF]

ERJ Open Res
Maniscalco M, Fuschillo S, Ambrosino P, Candia C, di Domenico A, Lombardi C, Motta A, Ambrosino N.   +7 more
europepmc   +1 more source

Nuclear Enlargement as a Histological Hallmark of Skeletal Muscle Aging, Revealed by Deep Learning-Driven Analysis and Validated in Inflammatory Myopathies. [PDF]

Aging Cell
Dao T, Nguyen TT, Hoang GM, Park J, Jo Y, Ngoc TH, Pho DH, Minh DT, Ton EA, Lee S, Kim HJ, Dung VC, Kim JG, Ryu D.   +13 more
europepmc   +1 more source

Decoding cellular communication networks and signaling pathways in bone, skeletal muscle, and bone-muscle crosstalk through spatial transcriptomics in a young male mouse. [PDF]

Bone Res
Qiu C, Li Y, Gong Y, Sherman W, Tian D, Lin W, Pan Z, Afolabi B, Thumbigere V, Su K, Deng J, Hou Y, Mungasavalli Gnanesh S, Luo Z, Tian Q, Sanchez F, Chen Y, Shen H, Deng HW.   +18 more
europepmc   +1 more source

Cell type–resolved transcriptomic map of skeletal muscle in women with polycystic ovary syndrome

Stener-Victorin E, Sparovec TG, Eriksson G, Schutten R, Li C, Lu H, Rosa J, Dahmani S, Torstensson S, Ohlsson C, Lindgren E, Damdimopoulou P, Hirschberg AL, Deng Q, Lindskog C.   +14 more
europepmc   +1 more source