Results 71 to 80 of about 362,047 (272)
Advanced Healthcare Materials, EarlyView.The scaffold‐free Anchored Cell Sheet Engineering platform is used to create three‐dimensional (3D) in vitro models of skeletal muscle tissue that replicate key features of Duchenne and Myotonic dystrophies. These personalized tissue models, validated by histological, immunostaining, and proteomics analyses, accurately mimic disease phenotypes and ...
Alireza Shahin‐Shamsabadi +1 more
wiley +1 more source
PPARδ regulates satellite cell proliferation and skeletal muscle regeneration
Skeletal Muscle, 2011 Peroxisome proliferator-activated receptors (PPARs) are a class of nuclear receptors that play important roles in development and energy metabolism. Whereas PPARδ has been shown to regulate mitochondrial biosynthesis and slow-muscle fiber types, its ...
Angione Alison R +4 more
doaj +1 more source
Investigating the correlation of muscle function tests and sarcomere organization in C. elegans
Skeletal Muscle, 2021 Background Caenorhabditis elegans has been widely used as a model to study muscle structure and function. Its body wall muscle is functionally and structurally similar to vertebrate skeletal muscle with conserved molecular pathways contributing to ...
Leila Lesanpezeshki +7 more
doaj +1 more source
A photo-click thiol-ene collagen-based hydrogel platform for skeletal muscle tissue engineering [PDF]
arXiv, 2023 UV-cured collagen-based hydrogels hold promise in skeletal muscle regeneration due to their soft elastic properties and porous architecture. However, the complex triple helix conformation of collagen and environmental conditions, i.e. molecular oxygen, pose risks to reaction controllability, wet-state integrity and reproducibility.
arxiv
Advanced Healthcare Materials, EarlyView.Volumetric muscle loss (VML) due to trauma or surgery, often leads to physical impairments. Traditional treatments rely on autologous flaps, limited by muscle availability often leading to donor site morbidity. This study presents multimodal bioprinting as an innovative approach for fabricating vascularized muscle flaps with 3D‐printed macrovessels ...
Eliana O. Fischer +8 more
wiley +1 more source
Inducible Cre transgenic mouse strain for skeletal muscle-specific gene targeting
Skeletal Muscle, 2012 Background The use of the Cre/loxP system for gene targeting has been proven to be a powerful tool for understanding gene function. The purpose of this study was to create and characterize an inducible, skeletal muscle-specific Cre transgenic mouse ...
McCarthy John J +4 more
doaj +1 more source
Multiscale Mechanical Modeling of Skeletal Muscle: A Systemic Review of the Literature [PDF]
Purpose: From the myofibrils to the whole muscle scale, muscle micro-constituents exhibit passive and active mechanical properties, potentially coupled to electrical, chemical, and thermal properties. Experimental characterization of some of these properties is currently not available for all muscle constituents.
arxiv +1 more source
Advanced Healthcare Materials, EarlyView.This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto +2 more
wiley +1 more source
Skeletal Muscle, 2017 Background Chronic increases in the levels of the inflammatory cytokine interleukin-6 (IL-6) in serum and skeletal muscle are thought to contribute to the progression of muscular dystrophy.
Eiji Wada +5 more
doaj +1 more source
Segmentation of Skeletal Muscle in Thigh Dixon MRI Based on Texture Analysis [PDF]
arXiv, 2019 Segmentation of skeletal muscles in Magnetic Resonance Images (MRI) is essential for the study of muscle physiology and diagnosis of muscular pathologies. However, manual segmentation of large MRI volumes is a time-consuming task. The state-of-the-art on algorithms for muscle segmentation in MRI is still not very extensive and is somewhat database ...
arxiv