Results 71 to 80 of about 2,572,202 (339)

Automated image-analysis method for the quantification of fiber morphometry and fiber type population in human skeletal muscle

Skeletal Muscle, 2019
Background The quantitative analysis of muscle histomorphometry has been growing in importance in both research and clinical settings. Accurate and stringent assessment of myofibers’ changes in size and number, and alterations in the proportion of ...
Perla C. Reyes-Fernandez, Baptiste Periou, Xavier Decrouy, Fréderic Relaix, François Jérôme Authier   +4 more
doaj   +1 more source

Optimized method for extraction of exosomes from human primary muscle cells

Skeletal Muscle, 2020
Skeletal muscle is increasingly considered an endocrine organ secreting myokines and extracellular vesicles (exosomes and microvesicles), which can affect physiological changes with an impact on different pathological conditions, including regenerative ...
Laura Le Gall, Zamalou Gisele Ouandaogo, Ekene Anakor, Owen Connolly, Gillian Butler Browne, Jeanne Laine, William Duddy, Stephanie Duguez   +7 more
doaj   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

FEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová, Tímea Kurdiová, Daria Barkova, Natália Pálešová, Jana Babulicová, Silvia Tyčiaková, Marta Novotová, Mária Balážová, Miroslav Sabo, Václav Pustka, Jozef Ukropec, Barbara Ukropcová   +11 more
wiley   +1 more source

Tissue-specific expression of high-voltage-activated dihydropyridine-sensitive L-type calcium channels [PDF]

, 1991
The cloning of the cDNA for the α1 subunit of L-type calcium channels revealed that at least two genes (CaCh1 and CaCh2) exist which give rise to several splice variants.
Caffrey J. M., Catterall W. A., Ellis S. B., Glossmann H., Grabner M., Hofmann F., Hoshi T., Jay S. D., Jongh K. S., Kim H. S., Koch W. J., Koch W. J., Melton D. A., Olson E. N., Perez-Reyes E., Rampe D. E., Reuter H., Ruth P., Ruth P., Sambrook J., Sanger F., Schubert D., Shih H.-T., Snutch T. P., Tanabe T., Thomas P. S., Tsien R. W.   +26 more
core   +2 more sources

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

FEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel, Mekala Gunasekaran, Audrey L. Daugherty, Natalya M. Wells, Johnnie Turner, Christine C. Bruels, Christina A. Pacak, Isabelle Draper, Peter B. Kang   +8 more
wiley   +1 more source

IIb or not IIb? Regulation of myosin heavy chain gene expression in mice and men

Skeletal Muscle, 2011
Background While the myosin heavy chain IIb isoform (MyHC-IIb) is the predominant motor protein in most skeletal muscles of rats and mice, the messenger RNA (mRNA) for this isoform is only expressed in a very small subset of specialized muscles in adult ...
Harrison Brooke C, Allen David L, Leinwand Leslie A   +2 more
doaj   +1 more source

Role of Myokines in Regulating Skeletal Muscle Mass and Function

Frontiers in Physiology, 2019
Loss of skeletal muscle mass and strength has recently become a hot research topic with the extension of life span and an increasingly sedentary lifestyle in modern society.
J. H. Lee, H. Jun
semanticscholar   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Differential requirement for satellite cells during overload-induced muscle hypertrophy in growing versus mature mice

Skeletal Muscle, 2017
Background Pax7+ satellite cells are required for skeletal muscle fiber growth during post-natal development in mice. Satellite cell-mediated myonuclear accretion also appears to persist into early adulthood.
Kevin A. Murach, Sarah H. White, Yuan Wen, Angel Ho, Esther E. Dupont-Versteegden, John J. McCarthy, Charlotte A. Peterson   +6 more
doaj   +1 more source

Haemangiomata of skeletal muscle

Journal of British Surgery, 1972
Abstract Two cases of skeletal muscle haemangiomata are described. All previous cases of this condition are reviewed and a brief account is given of the important facets of aetiology, diagnosis, and treatment. Wherever a soft-tissue swelling presents in the region of skeletal muscle the possible diagnosis of
openaire   +2 more sources