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Regulation of force in vascular smooth muscle
Journal of Molecular and Cellular Cardiology, 2003Vascular smooth muscle contraction plays a defining role in the regulation and maintenance of blood pressure, and its deregulation is associated with many clinical syndromes including hypertension, coronary vasospasm and congestive heart failure. Over the past 20 years, there has been a growing understanding of the regulation of 20 kDa myosin light ...
Ozgur, Ogut, Frank V, Brozovich
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Actomyosin of Human Vascular Smooth Muscle
Nature, 1966ACTOMYOSIN of vascular smooth muscle appears to be similar in certain properties to actomyosin of uterine smooth muscle1. These properties include solubility, viscosity (ATP sensitivity), and ATPase activity. Needham2 first observed that uterine actomyosin showed an elevated ATPase activity when the potassium chloride concentration was raised from 0.1 ...
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POTASSIUM CHANNELS IN VASCULAR SMOOTH MUSCLE
Clinical and Experimental Pharmacology and Physiology, 1996SUMMARY1. Regulation of smooth muscle membrane potential through changes in K+ channel activity and subsequent alterations in the activity of voltage‐dependent calcium channels is a major mechanism of vasodilation and vasoconstriction, both in normal and pathophysiological conditions.
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Oxidants and vascular smooth muscle
Biochemical Society Transactions, 1989M, Schachter +3 more
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Endothelium and responsiveness of vascular smooth muscle.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1988The endothelium of a wide variety of arteries can release a potent vasodilator substance (endothelium-derived relaxing factor). The relaxation of smooth muscle cells evoked by endothelium-derived relaxing factor is associated with activation of guanylate cyclase.
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Calcium and Sodium in Vascular Smooth Muscle
Annals of the New York Academy of Sciences, 1986A P, Somlyo, R, Broderick, A V, Somlyo
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