Results 21 to 30 of about 3,179,601 (345)
Distinct Roles of Smooth Muscle and Non-muscle Myosin Light Chain-Mediated Smooth Muscle Contraction
Frontiers in Physiology, 2020 Both smooth muscle (SM) and non-muscle (NM) myosin II are expressed in hollow organs such as the bladder and uterus, but their respective roles in contraction and corresponding physiological functions remain to be determined.
Jie Sun +13 more
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Fibronectin matrix polymerization regulates smooth muscle cell phenotype through a Rac1 dependent mechanism. [PDF]
PLoS ONE, 2014 Smooth muscle cells are maintained in a differentiated state in the vessel wall, but can be modulated to a synthetic phenotype following injury. Smooth muscle phenotypic modulation is thought to play an important role in the pathology of vascular ...
Feng Shi +4 more
doaj +1 more source
α8β1 integrin regulates nutrient absorption through an Mfge8-PTEN dependent mechanism. [PDF]
, 2016 Coordinated gastrointestinal smooth muscle contraction is critical for proper nutrient absorption and is altered in a number of medical disorders. In this work, we demonstrate a critical role for the RGD-binding integrin α8β1 in promoting nutrient ...
Atabai, Kamran +12 more
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Human tribbles-1 controls proliferation and chemotaxis of smooth muscle cells via MAPK signaling pathways [PDF]
, 2007 Migration and proliferation of smooth muscle cells are key to a number of physiological and pathological processes, including wound healing and the narrowing of the vessel wall.Previous work has shown links between inflammatory stimuli and vascular ...
Agnes Czibula +58 more
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Differentiation of multipotent vascular stem cells contributes to vascular diseases. [PDF]
, 2012 It is generally accepted that the de-differentiation of smooth muscle cells, from the contractile to the proliferative/synthetic phenotype, has an important role during vascular remodelling and diseases.
Chu, Julia S +7 more
core +1 more source
Journal of Pharmacological Sciences, 2005 Proteinases like thrombin and trypsin, long known for their ability to activate the coagulation cascade or to act as digestive enzymes for many protein targets, are now recognized as hormone-like regulators of cell function.
Morley D. Hollenberg
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Alteration of cystic airway mesenchyme in congenital pulmonary airway malformation. [PDF]
, 2019 Congenital pulmonary airway malformation (CPAM) is the most common congenital lesion detected in the neonatal lung, which may lead to respiratory distress, infection, and pneumothorax.
Jiang, Yi +9 more
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Neurogenic Inflammation of Guinea-Pig Bladder
Mediators of Inflammation, 1994 Capsaicin, substance P, and ovalbumin, instilled into the bladders of naive and ovalbumin (OVA) sensitized guineapigs caused inflammation, as indicated by increased vascular permeability.
D. E. Bjorling, M. R. Saban, R. Saban
doaj +1 more source
Journal of Pharmacological Sciences, 2004 A serine proteinase with kallikrein-like activity (LV-Ka) has been purified to homogeneity from bushmaster snake (Lachesis muta muta) venom. Physicochemical studies indicated that LV-Ka is a single chain glycoprotein with a molecular mass (Mr) of 33 kDa ...
Maria L.D. Weinberg +6 more
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Notch2 and Notch3 function together to regulate vascular smooth muscle development. [PDF]
PLoS ONE, 2012 Notch signaling has been implicated in the regulation of smooth muscle differentiation, but the precise role of Notch receptors is ill defined. Although Notch3 receptor expression is high in smooth muscle, Notch3 mutant mice are viable and display only ...
Qingqing Wang +3 more
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