Results 21 to 30 of about 445,296 (267)

Regulation of human airway smooth muscle cell migration and relevance to asthma

Respiratory Research, 2017
Airway remodelling is an important feature of asthma pathogenesis. A key structural change inherent in airway remodelling is increased airway smooth muscle mass.
Brittany Salter, Cara Pray, Katherine Radford, James G. Martin, Parameswaran Nair   +4 more
doaj   +1 more source

Generation of myogenic progenitor cell-derived smooth muscle cells for sphincter regeneration

Stem Cell Research & Therapy, 2020
Background Degeneration of smooth muscles in sphincters can cause debilitating diseases such as fecal incontinence. Skeletal muscle-derived cells have been effectively used in clinics for the regeneration of the skeletal muscle sphincters, such as the ...
Marco Thurner, Martin Deutsch, Katrin Janke, Franka Messner, Christina Kreutzer, Stanislav Beyl, Sébastien Couillard-Després, Steffen Hering, Jakob Troppmair, Rainer Marksteiner   +9 more
doaj   +1 more source

Orai store-operated Ca2+ entry channels modulate urethral smooth muscle contractility

Channels
In the European Union, urinary incontinence (UI) affects 45% of adults during their lifetime, representing a major clinical and socio-economic burden. Failure of urethral smooth muscle (USM) to contract normally (hypo or hypercontractility) contributes ...
Bernard T. Drumm, Neha Gupta
doaj   +1 more source

Acquired smooth muscle hamartoma: A case report on the lower extremity with hidrosis

SAGE Open Medical Case Reports, 2019
Smooth muscle hamartomas are benign dermal proliferations of smooth muscle cells. Smooth muscle hamartomas are sub-divided into congenital or acquired; the latter is a rare entity with less than 20 cases being reported in the English literature.
Malika A Ladha, Todd Remington
doaj   +1 more source

Masson Trichrome Stain Helps Differentiate Myofibroma from Smooth Muscle Lesions in the Head and Neck Region

Journal of the Formosan Medical Association, 2008
Myofibromas are well described in the head and neck region, but differentiating them from smooth muscle lesions is still difficult using smooth muscle immunohistochemical stains.
Julia Yu Fong Chang, Harvey P. Kessler
doaj   +1 more source

Smooth muscle raft-like membranes

Journal of Lipid Research, 2004
We developed a method for extracting raft-like, liquid-ordered membranes from the particulate fraction prepared from porcine trachealis smooth muscle.
Carl B. Baron, Ronald F. Coburn
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

ANO1 channels are expressed in mouse urethral smooth muscle but do not contribute to agonist or neurally evoked contractions

Scientific Reports
Anoctamin-1 Ca2+-activated Cl− channels (ANO1) are proposed to modulate contractility of urethra smooth muscle cells (USMC), but their cellular expression and contribution to agonist/neural evoked activity is unclear.
Neha Gupta, Salah A. Baker, Kenton M. Sanders, Kaneez E. Rabab, Denzel KF. Thean, Tuleen Alkawadri, Caoimhin S. Griffin, Gerard P. Sergeant, Mark A. Hollywood, Keith D. Thornbury, Bernard T. Drumm   +10 more
doaj   +1 more source

A Case of Massive Broad Ligament Leiomyoma Imitating an Ovarian Tumour [PDF]

Journal of Clinical and Diagnostic Research, 2014
Leiomyomas are the most common benign tumours of female reproductive system which occur in women of child- bearing ages. Large fibroids are known to arise from uterus, but rarely from broad ligament.
Preeti Bansal, Dinesh Garg
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source