Results 41 to 50 of about 788,671 (263)
Unique Contractile and Structural Protein Expression in Dog Ileal Inner Circular Smooth Muscle [PDF]
, 2009 This study was designed to test the hypothesis that there is heterogeneous expression of contractile and structural proteins between the smooth muscle cells (SMCs) in the inner and outer circular muscle (ICM and OCM) layers of the ileum ...
Eddinger, Thomas J.
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Regulation of smooth muscle dystrophin and synaptopodin 2 expression by actin polymerization and vascular injury [PDF]
, 2015 Producción CientíficaObjective: Actin dynamics in vascular smooth muscle is known to regulate contractile differentiation and may play a role in the pathogenesis of vascular disease. However, the list of genes regulated by actin polymerization in smooth
Albinsson, Sebastian +13 more
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Activation of smooth muscle myosin by smooth and skeletal muscle actins
FEBS Letters, 1981 It has been reported that actins from human uterine and from chicken gizzard smooth muscle are less effective than rabbit skeletal muscle actin in activating the Mg*+-ATPase activity of rabbit skeletal muscle myosin or heavy meromyosin (HMM, [ 1,2]). The difference has been shown to result from an -2-fold greater apparent dissociation constant (Kapp ...
Apolinary Sobieszek +1 more
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Smooth muscle hyperplasia of the epididymis [PDF]
Journal of Surgical Case Reports, 2011 Benign smooth muscle cell proliferation commonly involves a variety of body organs, yet is a rare finding in the spermatic cord or paratesticular tissue of the male genital tract. Here we discuss a case of smooth muscle hyperplasia of the epididymis which presented as an intrascrotal mass.
Anne Marie Pollock, D Douglas, O Blach
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Airway Smooth Muscle and Asthma
Cells, 2023 Airway smooth muscle (ASM) was first described in 1804 by Franz Daniel Reisseisen (as related by Otis (1983)) [...]
Steven An, Dale D. Tang
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Expression of Smooth Muscle Myosin Heavy Chains and Unloaded Shortening in Single Smooth Muscle Cells [PDF]
, 1997 The functional significance of the variable expression of the smooth muscle myosin heavy chain (SM-MHC) tail isoforms, SM1 and SM2, was examined at the mRNA level (which correlates with the protein level) in individual permeabilized rabbit arterial ...
Eddinger, Thomas, Meer, Daniel P.
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Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source