Results 51 to 60 of about 788,671 (263)

The gamma-smooth muscle actin isoform in smooth muscle and smooth muscle-like cells

, 2013
L'actine est non seulement la protéine la plus abondante dans la plupart des cellules eucaryotes mais également une des plus conservées dans l'évolution. Il reste toutefois à ce jour de nombreuses zones d'ombre, en particulier en ce qui concerne le rôle de ses différentes isoformes.
openaire   +2 more sources

Geometric and dosimetric evaluation of a commercial AI auto‐contouring tool on multiple anatomical sites in CT scans

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Current radiotherapy practices rely on manual contouring of CT scans, which is time‐consuming, prone to variability, and requires highly trained experts. There is a need for more efficient and consistent contouring methods. This study evaluated the performance of the Varian Ethos AI auto‐contouring tool to assess its potential integration into
Robert N. Finnegan, Alexandra Quinn, Patrick Horsley, Joseph Chan, Maegan Stewart, Regina Bromley, Jeremy Booth   +6 more
wiley   +1 more source

Free ureteral replacement in rats: regeneration of ureteral wall components in the acellular matrix graft. [PDF]

, 1997
ObjectivesTo evaluate ureteral replacement by a free homologous graft of acellular matrix in a rat model.MethodsIn 30 male Sprague-Dawley rats, a 0.3 to 0.8-cm midsegment of the left ureter was resected and replaced with an acellular matrix graft of ...
Dahiya, R, Dahms, SE, Lue, TF, Nunes, L, Piechota, HJ, Tanagho, EA   +5 more
core   +1 more source

Cortical Excitability Before and After Long‐Term Perampanel Treatment for Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Antiseizure medications (ASMs), which may influence cortical excitability, are the mainstay of epilepsy treatment. Transcranial magnetic stimulation (TMS) helps evaluate cortical excitability. We assessed changes in TMS responses using serial TMS measurements in people treated with an adjunctive noncompetitive AMPA‐receptor ...
Robert M. Helling, Johannes P. van Dijk, Prisca R. Bauer, Roland D. Thijs, Josemir W. Sander, Machiel Zwarts, Gerhard H. Visser   +6 more
wiley   +1 more source

Occurrence, Risk Factors, and Prognosis of Acute Cerebral Microinfarcts in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic cerebral small vessel disease in adults. This study investigates the occurrence, risk factors, and prognosis of acute cerebral microinfarcts (ACMIs) in patients with CADASIL.
Xuejiao Men, Hui Li, Zhuoxin Guo, Bin Qin, Hengfang Ruan, Ruipeng Cai, Bingjun Zhang, Aimin Wu, Lei Wei, Yongqiang Dai, Haiyan Li, Zhengqi Lu   +11 more
wiley   +1 more source

Smooth Muscle [PDF]

, 2008
Histology blog entry for September 13, 2008 about smooth ...
Krause, William J., II, 1942-
core  

Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden, Charles Carron, Donatienne Van Weehaeghe, Joke De Vocht, Fouke Ombelet, Pegah Masrori, Caro De Weerdt, Rebecca E. James, Lauren T. Evans, Frederick A. Schroeder, Jacob M. Hooker, Michel Koole, Janice E. Kranz, Tonya M. Gilbert, Philip Van Damme, Koen Van Laere   +15 more
wiley   +1 more source

Aspirin and glyceryl trinitrate effects on polyamine uptake and smooth muscle cell growth [PDF]

, 2004
This paper looks at aspirin and glyceryl trinitrate effects on polyamine uptake and smooth muscle cell ...
Clarke, Brendan, Grant, M.H., Kelso, K., Wallace, H.M., Winn, P.L.   +4 more
core  

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

Advanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang, Lijuan Zhang, Jiaorong Tan, Fei Li, Yishan Jin, Limei He, Xin Yang   +6 more
wiley   +1 more source

MMP-1 activation contributes to airway smooth muscle growth and asthma severity [PDF]

, 2016
Introduction: Matrix metalloproteinase-1 and mast cells are present in the airways of people with asthma. We hypothesised that matrix metalloproteinase-1 could be activated by mast cells and increase asthma severity.
Berger P, Catherine Reynolds, Charlotte K. Billington, Christopher Philp, David J. Jackson, Debbie Clements, Dominick E. Shaw, Hasaneen NA, Irshad Soomro, Johnson S, Karlinsky JB, Naveed S, Rajah R, Sebastian L. Johnston, Shams-un-nisa Naveed, Simon R. Johnson, Timothy W. Harrison   +16 more
core   +2 more sources