Results 61 to 70 of about 788,671 (263)

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

Maintenance of GLUT4 expression in smooth muscle prevents hypertension‐induced changes in vascular reactivity [PDF]

open access: yes, 2015
Previous studies have shown that expression of GLUT4 is decreased in arterial smooth muscle of hypertensive rats and mice and that total body overexpression of GLUT4 in mice prevents enhanced arterial reactivity in hypertension.
Atkins, Kevin B.   +5 more
core   +1 more source

Shape Memory Polymer‐Based Hook‐and‐Loop Fastener for Robust Bonding and on‐Demand Easy Separation

open access: yesAdvanced Engineering Materials, EarlyView.
A 3D shape memory polymer‐based hook‐and‐loop fastener, fabricated using projection microstereolithography and molding, offers tunable bonding strength through temperature control. When heated from 25 to 70 °C, the fastener softens and deforms easily, reducing bonding strength by 20‐fold for on‐demand easy separation.
Chen Yang   +5 more
wiley   +1 more source

Endothelial and smooth muscle cell interactions with a PCL-PU composite vascular scaffold with potential for bioactive release [PDF]

open access: yes, 2006
Paper discussing endothelial and smooth muscle cell interactions with a PCL-PU composite vascular scaffold with potential for bioactive ...
Black, Richard   +2 more
core  

Forkhead box F2 Regulation of Platelet-Derived Growth Factor and myocardin/Serum Response Factor Signaling is Essential for Intestinal Development [PDF]

open access: yes, 2015
Alterations in the forkhead box F2 gene expression have been reported in numerous pathologies, and Foxf2−/− mice are perinatal lethal with multiple malformations; however, molecular mechanisms pertaining to Foxf2 signaling are severely lacking.
Bolte, Craig   +8 more
core   +1 more source

3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies

open access: yesAdvanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht   +5 more
wiley   +1 more source

Involvement of STAT3 in Bladder Smooth Muscle Hypertrophy Following Bladder Outlet Obstruction [PDF]

open access: yes, 2006
We examined the involvement of the signal transducer and activator of transcription 3 (STAT3) in bladder outlet obstruction (BOO)-induced bladder smooth muscle hypertrophy using a rat in vivo and in vitro study.
Asanuma, Masato   +5 more
core   +1 more source

Airway Smooth Muscle and Asthma

open access: yesAllergology International, 2006
The airway smooth muscle is the key determinant of airway narrowing in asthma but its function in the absence of disease is unknown. Evidence for an intrinsic abnormality in the muscle in asthma is only just emerging. The airway smooth muscle is not merely a contractile cell, but also one which determines the composition of, and interacts with the ...
Judith L. Black, Brian G. Oliver
openaire   +4 more sources

A Novel Protein‐Polysaccharide Oral Nanoemulsion Targeting Activated Hepatic Stellate Cells to Enhance the Therapeutic Effect of Pirfenidone on Fibrosis After Transarterial Chemoembolization for Liver Cancer

open access: yesAdvanced Functional Materials, EarlyView.
Transarterial Chemoembolization (TACE) may aggravate liver fibrosis. In this study, a novel oral targeting nanoemulsion is fabricated to enhance the therapeutic effect of antifibrotic drug‐pirfenidone (PFD) on fibrosis after TACE. Studies have shown that PFD nanoemulsion can enhance the oral liver targeting effect of PFD, and effectively improve the ...
Zhimei Cheng   +12 more
wiley   +1 more source

Muscarinic M2 acetylcholine receptor distribution in the guinea-pig gastrointestinal tract [PDF]

open access: yes, 2006
In the enteric nervous system, acetylcholine is the most common neurotransmitter to induce gastrointestinal smooth muscle contractions. Cholinergic signaling is mediated by muscarinic acetylcholine receptors on the surface of smooth muscle cells.
58998   +3 more
core   +1 more source

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