Results 161 to 170 of about 2,151,009 (319)

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source

Adiponectin-receptor agonism prevents right ventricular tissue pathology in a mouse model of Duchenne muscular dystrophy

Molecular Metabolism
Objective: Cardiac fibrosis during Duchenne muscular dystrophy (DMD) arises from cellular damage and inflammation and is associated with metabolic dysfunction.
Shivam Gandhi, Luca J. Delfinis, Parashar D. Bhatt, Madison C. Garibotti, Catherine A. Bellissimo, Amireza N. Goli, Brooke A. Morris, Aditya N. Brahmbhatt, Simona Yakobov-Shimonov, Fasih A. Rahman, Joe Quadrilatero, Jeremy A. Simpson, Gary Sweeney, Ali A. Abdul-Sater, Peter H. Backx, Henry H. Hsu, Christopher G.R. Perry   +16 more
doaj  

Klf9 Loss of Function Protects Against Glucocorticoids Induced Skeletal Muscle Wasting. [PDF]

J Cachexia Sarcopenia Muscle
Zhang Y, Hao J, Feng Y, Qiu T, Wu J, Zhou X, Fan H, Chang Y.   +7 more
europepmc   +1 more source

THE PENETRATION OF SOME CATIONS INTO MUSCLE [PDF]

, 1959
L. J. Mullins
openalex   +1 more source

Key Trends and Insights in Smart Polymeric Skin Wearable Patches

Advanced Engineering Materials, EarlyView.
Intelligent polymers, which respond to various physical and biological stimuli, are explored for the development of skin wearable patches in biomedical applications. Smart polymers, also known as intelligent or stimuli‐responsive polymers, play a crucial role in the development of advanced wearable patches due to their versatility and softness.
Sergio J. Peñas‐Núñez, Rajat Rai, Miryam Criado‐Gonzalez   +2 more
wiley   +1 more source

Late-Stage Skeletal Muscle Transcriptome in Duchenne Muscular Dystrophy Shows a BMP4-Induced Molecular Signature. [PDF]

J Cachexia Sarcopenia Muscle
Sothers H, Hu X, Crossman DK, Si Y, Alexander MS, McDonald MN, King PH, Lopez MA.   +7 more
europepmc   +1 more source

Cation Accumulation by Muscle Tissue: The Displacement of Potassium by Rubidium and Cesium in the Living Animal12 [PDF]

, 1957
Arnold S. Relman, Anne T. Lambie, Belton A. Burrows, Arlene M. Roy   +3 more
openalex   +1 more source

Reliable Tissue Grasping in Robotic Minimally Invasive Surgery Enabled by Optical‐Based Slip Sensing

Advanced Engineering Materials, EarlyView.
An optical‐based slip sensing method using a complementary metal–oxide–semiconductor image sensor with a built‐in infrared light emitting diode enables real‐time detection of tissue slippage—including displacement, direction, and speed—in robotic minimally invasive surgery.
Minjae Lee, Amy Kyungwon Han
wiley   +1 more source

Thigh Muscles and Metabolic Dysfunction-Associated Steatotic Liver Disease: Findings From the SCAPIS/IGT-Microbiota Study. [PDF]

Liver Int
Osmancevic A, Gummesson A, Allison M, Kullberg J, Li Y, Bergström G, Daka B.   +6 more
europepmc   +1 more source

3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht, Majd Machour, Inbal Michael, Maria Bulatova, Janette Zavin, Shulamit Levenberg   +5 more
wiley   +1 more source