Results 81 to 90 of about 3,840,047 (388)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Comparison of Architectural and Performance Adaptations of Hip Extension Exercise Under Gravitational or Inertial Loading Conditions: A Randomized Controlled Trial

European Journal of Sport Science
Increasing the length of the biceps femoris long head (BFlh) fascicle is one of the objectives of hamstring injury prevention programs. This study aimed to investigate training‐induced adaptations in BFlh architecture and performance measures after a six‐
Rodrigo Martín‐San Agustín, Lorenzo Castillo‐Ballesta, Rubén Esbri‐Navarro, Javier Herraiz‐ Garvín   +3 more
doaj   +1 more source

The Hamstrings: Anatomic and Physiologic Variations and Their Potential Relationships With Injury Risk

Frontiers in Physiology, 2021
The incidence and recurrence of hamstrings injuries are very high in sports, posing elevated performance and financial-related costs. Attempts to identify the risk factors involved in predicting vulnerability to hamstrings injury is important for ...
José Afonso, Sílvia Rocha-Rodrigues, Sílvia Rocha-Rodrigues, Sílvia Rocha-Rodrigues, Filipe M. Clemente, Filipe M. Clemente, Michele Aquino, Pantelis T. Nikolaidis, Hugo Sarmento, Alberto Fílter, Alberto Fílter, Jesús Olivares-Jabalera, Jesús Olivares-Jabalera, Rodrigo Ramirez-Campillo, Rodrigo Ramirez-Campillo   +14 more
doaj   +1 more source

A haptic-enabled multimodal interface for the planning of hip arthroplasty [PDF]

, 2006
Multimodal environments help fuse a diverse range of sensory modalities, which is particularly important when integrating the complex data involved in surgical preoperative planning.
Caldwell, DG, Gray, JO, Petrone, M, Testi, D, Tsagarakis, NG, Viceconti, M, Zannoni, C   +6 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Additional heads of dorsal interosseous muscle in Caucasian cadavers and their clinical significance

Sahel Medical Journal, 2013
Dorsal interossei are group of four intrinsic muscles of the hand that are of immense importance in its day-to-day functions. The finding of any variation related to these muscles is of significance from point of view of hand surgeons.
Vaishaly Kishore Bharambe, Sapna Prashant Shevde, Vatsalaswamy Puranam, Nilesh Subhash Kanaskar   +3 more
doaj   +1 more source

The multi-functional foot in athletic movement: Extraordinary feats by our extraordinary feet [PDF]

, 2016
The unique architecture of the foot system provides a sensitive, multi-tensional method of communicating with the surrounding environment. Within the premise of the paper, we discuss three themes: complexity, degeneracy and bio-tensegrity.
Kiely, J, Wilson, J
core   +2 more sources

Rate of Force Development and Muscle Architecture after Fast and Slow Velocity Eccentric Training

Sports, 2019
The aim of the study was to investigate the rate of force development (RFD) and muscle architecture early adaptations in response to training with fast- or slow-velocity eccentric squats.
Angeliki-Nikoletta Stasinaki, Nikolaos Zaras, Spyridon K. Methenitis, G. Bogdanis, G. Terzis   +4 more
semanticscholar   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Are mice good models for human neuromuscular disease? Comparing muscle excursions in walking between mice and humans [PDF]

, 2017
The mouse is one of the most widely used animal models to study neuromuscular diseases and test new therapeutic strategies. However, findings from successful pre-clinical studies using mouse models frequently fail to translate to humans due to various ...
A De Luca, A Rajagopal, A Soman, AA Biewener, AA Biewener, AC Ludolph, AEH Emery, AL Camp, AV Birn-Jeffery, BH Wokke, BJ Petrof, C Pastoret, C Webster, CM Consolino, CM Eng, DM Escolar, E Azizi, E Mok, EK Moo, EM Arnold, EM Arnold, EM Arnold, FA Jenkins, FE Zajac, GM Buyse, GT Carter, H Radley-Crabb, H Stedman, HB van der Worp, HM Hsieh-Li, IG Kirkinezos, J Manning, JA Granchelli, JA Vilensky, JH Veldink, JJ Kaczor, JK Mah, JN Kornegay, JN Kornegay, JP Charles, JP Charles, JR Chamberlain, JW Carnwath, JW McGreevy, KA Clarke, KN An, L Xu, LM Ittner, M Benatar, M Bodor, M Millard, MD Grounds, MD Klein Horsman, ME Gurney, ME Llewellyn, MP Kadaba, N Alexander, N Serradj, NP Whitehead, P DeVita, P Moens, P Sicinski, R Burdi, R Willmann, R Willmann, RH Miller, RW Burgess, SL Delp, SL Delp, SR Ward, SS Blemker, SV Brooks, T Akay, TA McMahon, TA Partridge, TS Buchanan, V Brussee, VC Henderson, X Chen, X Chen, X Hu, ZJ Domire   +81 more
core   +3 more sources