Results 71 to 80 of about 2,965,501 (292)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Effects of a 7-day step taper, training cessation, and retraining on lower body physical and morphological aspects in elite female ice hockey players

Frontiers in Sports and Active Living
PurposeThis study investigated the effects of a 7-day step taper before a national championship, followed by 2 weeks of training cessation and 2 weeks of retraining on lower body physical and morphological aspects.MethodsSeven elite female ice hockey ...
Daichi Nishiumi, Daichi Yamashita, Takanori Kurokawa, Naoki Hirase, Kazuki Wakamiya, Iñigo Mujika, Iñigo Mujika, Norikazu Hirose   +7 more
doaj   +1 more source

System Architecture for Home Muscle Rehabilitation Treatment

, 2022
The constant loss of functional capacity due to aging is a serious problem that can severely worsen the quality of life. Among the possible treatments, muscles electrostimulation can be a viable option because it is cheap and easy to access. With the evolution of wearable devices and the Internet of Things, this paper proposes a system architecture ...
Tiago Franco, Pedro Rangel Henriques, Paulo Alves, Maria João Varanda Pereira, Tiago Pedrosa, F. Silva, Paulo Leitão, L. Oliveira   +7 more
openaire   +2 more sources

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera, Agnese Tamanti, Silvia Messina, Nicola Dall'Osto, Teresa Maltempo, Stefano Ziccardi, Matteo Foschi, Maria Grazia Piscaglia, Diana Ferraro, Francesco Crescenzo, Francesca Rossi, Albulena Bajrami, Sabrina Marangoni, Damiano Marastoni, Francesca Benedetta Pizzini, Maria Isabel Leite, Roberta Magliozzi, Patrick Waters, Massimiliano Calabrese, Jacqueline Palace, Ruth Geraldes   +20 more
wiley   +1 more source

Effects of Lift Velocity on Muscle Activation During Leg Extension [PDF]

, 2013
It is not known if manipulating velocity within a prescribed resistance training mode will improve muscle activation. Muscle activations of the Rectus Femoris (RF), Vastus Lateralis (VL), Vastus Medialis (VM) and Bicep Femoris (BF) were examined during a
Johnson, Scott, Hatzel, Brian, Glass, Stephen C., Sjoquist, Heather   +3 more
core  

Morphological and functional characteristics of the muscle-tendon unit

Journal of Physical Fitness and Sports Medicine, 2012
The biomechanical features of skeletal muscles are reviewed, with regard to their form and function and anatomical components (fascicles and tendinous tissues).
Yasuo Kawakami
doaj   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

Rethinking the physiological cross-sectional area of skeletal muscle reveals the mechanical advantage of pennation

Royal Society Open Science
The shape of skeletal muscle varies remarkably—with important implications for locomotor performance. In many muscles, the fibres are arranged at an angle relative to the tendons’ line of action, termed the pennation angle.
Robert Rockenfeller, Michael Günther, Christofer J. Clemente, Taylor J. M. Dick   +3 more
doaj   +1 more source