Results 81 to 90 of about 339,817 (301)

Morphological and functional characteristics of the muscle-tendon unit

Journal of Physical Fitness and Sports Medicine, 2012
The biomechanical features of skeletal muscles are reviewed, with regard to their form and function and anatomical components (fascicles and tendinous tissues).
Yasuo Kawakami
doaj   +1 more source

Towards a Reconfigurable Sense-and-Stimulate Neural Interface Generating Biphasic Interleaved Stimulus [PDF]

, 2007
Published ...
Constandinou, T G, Drakakis, E M, Eftekhar, A, Toumazou, C, Triantis, I F   +4 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Circulating Tumor Necrosis Factor Alpha May Modulate the Short-Term Detraining Induced Muscle Mass Loss Following Prolonged Resistance Training

Frontiers in Physiology, 2019
IntroductionTumor necrosis factor alpha (TNFα) is a pro-inflammatory cytokine that has been shown to modulate muscle mass, and is responsive to exercise training.
Gerard McMahon, Gerard McMahon, Christopher I. Morse, Keith Winwood, Adrian Burden, Gladys L. Onambélé   +5 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Rethinking the physiological cross-sectional area of skeletal muscle reveals the mechanical advantage of pennation

Royal Society Open Science
The shape of skeletal muscle varies remarkably—with important implications for locomotor performance. In many muscles, the fibres are arranged at an angle relative to the tendons’ line of action, termed the pennation angle.
Robert Rockenfeller, Michael Günther, Christofer J. Clemente, Taylor J. M. Dick   +3 more
doaj   +1 more source

Form and Data - from linear Calculus to cybernetic Computation and Interaction [PDF]

, 2019
Digital architecture developed in the 1960s and, supported by CAAD the 1990s, has created the path towards an architecture produced by computer and architect in a mutual relationship.
Werner, Liss C.
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

System Architecture for Home Muscle Rehabilitation Treatment

, 2022
The constant loss of functional capacity due to aging is a serious problem that can severely worsen the quality of life. Among the possible treatments, muscles electrostimulation can be a viable option because it is cheap and easy to access. With the evolution of wearable devices and the Internet of Things, this paper proposes a system architecture ...
Tiago Franco, Pedro Rangel Henriques, Paulo Alves, Maria João Varanda Pereira, Tiago Pedrosa, F. Silva, Paulo Leitão, L. Oliveira   +7 more
openaire   +2 more sources

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source