Results 21 to 30 of about 5,886 (255)

Randomized double-blind personalized N-of-1 clinical trial to test the safety and potential efficacy of TJ-68 for treating muscle cramps in amyotrophic lateral sclerosis (ALS): study protocol for a TJ-68 trial

Trials, 2023
Introduction/aims Muscle cramps are a common and often disabling symptom in amyotrophic lateral sclerosis (ALS), a devastating and incurable neurodegenerative disorder.
Hiroshi Mitsumoto, Ken Cheung, Björn Oskarsson, Howard F. Andrews, Grace E. Jang, Jinsy A. Andrews, Jaimin S. Shah, Joseph Americo Fernandes, Martin McElhiney, Regina M. Santella   +9 more
doaj   +1 more source

Are electrically induced muscle cramps able to increase the cramp threshold frequency, when induced once a week?

Orthopedic Reviews, 2015
The cramp threshold frequency (CTF) is known to be positively correlated with the individual cramp susceptibility. Here we assessed CTF changes after two bouts of electrically induced muscle cramps (EIMCs).
Michael Behringer, Tobias Walter Link, Johannes Caspar Konrad Montag, Molly Leigh McCourt, Joachim Mester   +4 more
doaj   +1 more source

Ayurvedic Modalities and Shamana Chikitsa in the Management of Writer’s Cramp Syndrome: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Writer’s cramp syndrome is an uncommon handwriting disorder characterised by involuntary upper limb spasms and tremors in the hands. Most patients adopt unusual wrist and finger postures, using excessive force when holding and pressing the pen to the ...
Mahesh Sharma, Sourabh Deshmukh, Trupti Thakre, Nitika Senger   +3 more
doaj   +1 more source

Effect of Modified Burger Allen Exercise with Moist Heat Application on Leg Cramps and Fatigue among Pregnant Women [PDF]

Egyptian Journal of Health Care
Background: Leg cramps and fatigue are among the most prevalent discomforts of pregnancy, which can adversely affect sleep quality, physical activity, and overall maternal well-being.
Asmaa Ibrahim Abd El-Bary Marak, Hala Hamed Mohamed Elbastawesy, Nadia Mahmoud Mohammed Mahmoud   +2 more
doaj   +1 more source

Effect of Intradialytic Exercises on Muscle Cramps and Fatigue among Children Undergoing Hemodialysis [PDF]

Tanta Scientific Nursing Journal
Background: Children undergoing hemodialysis often suffer from negative effects such as muscle cramps, arrhythmias, nausea, vomiting, low blood pressure, and fatigue.
Yahia Sayed, Shaima Mohamed, Nagwa Abu-Elenen   +2 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Examining the impact of Buerger-Allen exercises on alleviating muscle cramps in extubated patients

Journal of Integrative Nursing
Objective: This study aimed to evaluate the effectiveness of Buerger-Allen exercise (BAE) in reducing muscle cramps among recently extubated patients in the intensive care unit (ICU).
Sahoo Rashmita, Swain Mamata, Tripathy Pravati   +2 more
doaj   +1 more source

Exercise muscle damage: the role of ACTN3 gene polymorphism

Спортивная медицина: наука и практика, 2020
Even the most experienced athletes are not safe from various types of muscle damage (cramp, contracture, sprain, tear and tear of the muscle). Nowadays, certain gene variations or polymorphisms associated with muscle damage caused by exercise are known ...
E. V. Orekhovskaya, A. V. Minin
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source