Results 31 to 40 of about 520,075 (309)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Clinical Outcomes of Bipolar Hemiarthroplasty with a Conjoined Tendon-Preserving Posterior Approach for Femoral Neck Fractures

Medicina
Background and Objectives: The conventional posterior approach in the lateral decubitus position is widely used for femoral neck fractures in femoral hemiarthroplasty. Postoperative dislocation is the major problem with this approach.
Hidetatsu Tanaka, Yu Mori, Atsushi Noro, Toshihisa Yano, Toshimi Aizawa, Keiji Masuda   +5 more
doaj   +1 more source

Transgenic overexpression of heat shock protein 72 in mouse muscle protects against exhaustive exercise-induced skeletal muscle damage

Journal of the Formosan Medical Association, 2013
Lifelong overexpression of heat shock protein (HSP) 72 in skeletal muscle is known to protect against age-related oxidative stress and muscle damage. This study aimed to ascertain whether exhaustive exercise (EE)-induced muscle fatigue and damage can be ...
Chieh-Chung Liu, Cheng-Hsien Lin, Chuan-Yi Lin, Ching-Cheng Lee, Mao-Tsun Lin, Hsiao-Chuan Wen   +5 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Association between Gray-Scale Ultrasound Imaging and Serological Creatine Kinase for Quantifying Exercise-Induced Muscle Damage: An Observational Study

Bioengineering, 2023
Limited evidence has verified if ultrasound imaging (US) can detect post-exercise muscle damage based on size, shape, and brightness metrics. This study aimed to analyze the correlation between creatine kinase (CK) concentration and (as a biomarker of ...
Jorge Buffet-García, Davinia Vicente-Campos, Mónica López-Redondo, Sandra Sánchez-Jorge, Javier Álvarez-González, Gustavo Plaza-Manzano, Tamara Seijas-Fernández, Juan Antonio Valera-Calero   +7 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Effects of cumulative school soccer matches separated by 24-h or 48-h interval on physical recovery status of U-19 players

Revista Brasileira de Cineantropometria e Desempenho Humano, 2021
This study aimed to evaluate the effects of cumulative school soccer matches separated by 24-h or 48-h intervals on recovery status of U-19 players. Thirty-four school athletes (17.6 ± 1.1 years) who played an U-19 school soccer competition (composed of ...
Vitor Hugo Santos Rezende, Diego A. Borba, Lucas A. Souza, Suene F. N. Chaves, Maria H. A. Pinheiro, Hugo C. Martins Costa, Daniel B. Coelho, Rauno A. P. Simola, Carlos M. A. Costa, André Bonadias Gadelha   +9 more
doaj  

Myotoxicity of telbivudine in pre-existing muscle damage

Virology Journal, 2010
Objectives It is unknown if telbivudine causes muscle damage only in patients with pre-existing muscle pathology. Case report A 27 yo male of African origin received telbivudine for hepatitis B during 3 months. Three weeks after initiation of the drug he
Ay Leyla, Finsterer Josef
doaj   +1 more source

Intramuscular Bleeding and Formation of Microthrombi during Skeletal Muscle Damage Caused by a Snake Venom Metalloprotease and a Cardiotoxin

Toxins, 2023
The interactions between specific snake venom toxins and muscle constituents are the major cause of severe muscle damage that often result in amputations and subsequent socioeconomic ramifications for snakebite victims and/or their families.
Medha Sonavane, José R. Almeida, Elanchezhian Rajan, Harry F. Williams, Felix Townsend, Elizabeth Cornish, Robert D. Mitchell, Ketan Patel, Sakthivel Vaiyapuri   +8 more
doaj   +1 more source

Modulation of Vascular Smooth Muscle Cell Multiplication, Apoptosis, and Inflammatory Damage by miR-21 in Coronary Heart Disease [PDF]

, 2021
Wei Liu, Yilin Li, Dongming Zhao
openalex   +1 more source