Annals of Neurology, EarlyView.Objective Spinocerebellar ataxia 1 (SCA1) is a fatal hereditary neurodegenerative disorder with no approved therapies, and gene‐targeting strategies have thus far failed in clinical trials. Exercise remains the only intervention shown to provide clinical benefit in patients with spinocerebellar ataxias (SCAs), yet the underlying mechanisms remain ...
Isabel Soto +12 more
wiley +1 more source
Ageing exacerbates the adverse effects of respiratory muscle fatigue on vascular function, locomotor muscle fatigue and exercise performance in males. [PDF]
Exp PhysiolMons V +4 more
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Annals of Neurology, EarlyView.Objective To evaluate the effectiveness and safety of ocrelizumab in self‐identified black and Hispanic people with relapsing multiple sclerosis. Methods The Characterization of Ocrelizumab in Minorities with Multiple Sclerosis (CHIMES) trial, a prospective, open‐label, single‐arm, phase 4 study, intentionally recruited underrepresented populations in ...
Lilyana Amezcua +16 more
wiley +1 more source
[Cluster-guided adaptive Transformer for muscle fatigue prediction]. [PDF]
Sheng Wu Yi Xue Gong Cheng Xue Za ZhiFan B, Bao X, Ding L, Wu J.
europepmc +1 more source
Three‐dimensional geometric morphometric analysis of diaphragmatic dome motion in COPD patients
The Anatomical Record, EarlyView.Abstract Diaphragmatic dysfunction is a hallmark of chronic obstructive pulmonary disease (COPD), especially in emphysema, where hyperinflation alters diaphragm geometry and impairs inspiratory mechanics. However, quantitative three‐dimensional (3D) assessments of diaphragmatic dome shape and motion across COPD phenotypes are limited.
José M. López‐Rey +5 more
wiley +1 more source
Retraction: The impact of COVID-19 and muscle fatigue on cardiorespiratory fitness and running kinetics in female recreational runners. [PDF]
Front PhysiolFrontiers Editorial Office.
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The 9+ month marathon: How pregnancy may have shaped human endurance capacities
The Anatomical Record, EarlyView.Abstract Anthropology has long considered the evolution of our uniquely human endurance capacities to be the result of selection upon anatomical and physiological features imposed by the demands of thermoregulation and resource acquisition, particularly during the demands of persistence hunting. Research has focused on the anatomical changes present in
Cara Ocobock
wiley +1 more source
Effects of kinesio taping applied over the biceps muscle on muscle activity and muscle fatigue. [PDF]
BMC Sports Sci Med RehabilBebek G, Ocak Y, Sözen H.
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The fossil record stays silent: Confusions and conundrums for hominin pelvis evolution
The Anatomical Record, EarlyView.Abstract The evolution of the hominin pelvis is commonly modeled as a series of stages driven largely by the requirements of bipedal locomotion, reproduction, thermoregulation, and pelvic floor muscular support. These patterns are complicated by variation in canal dimensions in relationship with different changes in overall pelvic breadths. To quantify
Helen K. Kurki, Cara M. Wall‐Scheffler
wiley +1 more source
Machine Learning-Driven Muscle Fatigue Estimation in Resistance Training with Assistive Robotics. [PDF]
Sensors (Basel)Baek JY, Kwon JH, Khan H, Lee MC.
europepmc +1 more source