Results 21 to 30 of about 13,059 (220)
Ca2+ activation of troponin C‐extracted vertebrate striated fast‐twitch muscle fibers [PDF]
Dual regulation Myosin‐linked control Troponin C Calcium switch Muscle contraction Cross‐bridge mechanism Weak bridge Strong bridge
Babu, Aravind +2 more
openaire +2 more sources
The enzymatic complex Nicotinamide Adenine Dinucleotide Phosphate (NADPH) oxidase (NOx) may be the principal source of reactive oxygen species (ROS). The NOX2 and NOX4 isoforms are tissue-dependent and are differentially expressed in slow-twitch fibers ...
Juliana Osório Alves +10 more
doaj +1 more source
Regulation of ClC-1 and KATP channels in action potential–firing fast-twitch muscle fibers [PDF]
Action potential (AP) excitation requires a transient dominance of depolarizing membrane currents over the repolarizing membrane currents that stabilize the resting membrane potential. Such stabilizing currents, in turn, depend on passive membrane conductance (Gm), which in skeletal muscle fibers covers membrane conductances for K+ (GK) and Cl− (GCl ...
Thomas Holm, Pedersen +4 more
openaire +3 more sources
MiR-208b Regulates the Conversion of Skeletal Muscle Fiber Types by Inhibiting Mettl8 Expression
Skeletal muscle, the main source of animal meat products, contains muscle fiber as a key unit. It is well known that transformation takes place between different types of muscle fibers, however, the conversion mechanism is not clear. In a previous study,
Xiang Li +3 more
doaj +1 more source
Need for speed: Human fast-twitch mitochondria favor power over efficiency
Objective: Human skeletal muscle consists of a mixture of slow- and fast-twitch fibers with distinct capacities for contraction mechanics, fermentation, and oxidative phosphorylation.
Sebastian Edman +3 more
doaj +1 more source
Muscle Fiber Type Transitions with Exercise Training: Shifting Perspectives
Human muscle fibers are generally classified by myosin heavy chain (MHC) isoforms characterized by slow to fast contractile speeds. Type I, or slow-twitch fibers, are seen in high abundance in elite endurance athletes, such as long-distance runners and ...
Daniel L. Plotkin +3 more
doaj +1 more source
Cycle Training Increased GLUT4 and Activation of Mammalian Target of Rapamycin in Fast Twitch Muscle Fibers [PDF]
To determine whether cycle training of sedentary subjects would increase the expression of the principle muscle glucose transporters, six volunteers completed 6 wk of progressively increasing intensity stationary cycle cycling.In vastus lateralis muscle biopsies, changes in expression of GLUT1, GLUT4, GLUT5, and GLUT12 were compared using quantitative ...
Stuart, Charles A. +6 more
openaire +3 more sources
The effect of 2-week, high-intensity running and a 2-week immobilization on muscle fiber type composition of the plantaris muscle from 18 female, 6-month-old Wistar rats (running, n = 6; immobilization, n = 6; sedentary control, n = 6) was bio- and ...
Eli Carmeli, Tal Gal Haimovitch
doaj +1 more source
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang +7 more
wiley +1 more source
Comparative analysis of the transcriptomes of EDL, psoas, and soleus muscles from mice
Background Individual skeletal muscles have evolved to perform specific tasks based on their molecular composition. In general, muscle fibers are characterized as either fast-twitch or slow-twitch based on their myosin heavy chain isoform profiles.
Pabodha Hettige +3 more
doaj +1 more source

