Histochemical Differentiation of Fibers in the Rat Slow and Fast Twitch Muscles.
Wistar male rats were sacrificed at 1, 3, 5, 7, 9, 11, 13, 15, 17, 19, and 21 days, and at 5 and 10 weeks of age. The histochemical differentiation of slow twitch soleus and fast twitch plantaris muscle fibers was examined from the enzyme activities of adenosine triphosphatase (slow- or fast-contracting), succinate dehydrogenase (high- or low-oxidative)
ISHIHARA, Akihiko, TAGUCHI, Sadayoshi
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LncRNA-FKBP1C regulates muscle fiber type switching by affecting the stability of MYH1B
Long non-coding RNAs (lncRNAs) are well-known to participate in a variety of important regulatory processes in myogenesis. In our previous RNA-seq study (accession number GSE58755), we found that lncRNA-FKBP1C was differentially expressed between White ...
Jia-ao Yu +5 more
doaj +1 more source
DNA methylation assessment from human slow- and fast-twitch skeletal muscle fibers [PDF]
A new application of the reduced representation bisulfite sequencing method was developed using low-DNA input to investigate the epigenetic profile of human slow- and fast-twitch skeletal muscle fibers. Successful library construction was completed with as little as 15 ng of DNA, and high-quality sequencing data were obtained with 32 ng of DNA ...
Gwénaëlle, Begue +3 more
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Drug Effect Unveils Inter-head Cooperativity and Strain-dependent ADP Release in Fast Skeletal Actomyosin [PDF]
Amrinone is a bipyridine compound with characteristic effects on the force-velocity relationship of fast skeletal muscle, including a reduction in the maximum shortening velocity and increased maximum isometric force.
Torres, Nuria Albet, +40 more
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Ca2+ activation of troponin C‐extracted vertebrate striated fast‐twitch muscle fibers [PDF]
Dual regulation Myosin‐linked control Troponin C Calcium switch Muscle contraction Cross‐bridge mechanism Weak bridge Strong bridge
Babu, Aravind +2 more
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Structure of the rabbit fast-twitch skeletal muscle calsequestrin gene [PDF]
We have isolated two overlapping 17-kilobase (kb) genomic clones which, together, encode the rabbit fasttwitch skeletal muscle calsequestrin. The calsequestrin gene is 8.6 kb in length and consists of 11 exons. Sl nuclease protection and primer extension
MacLennan, D. H. +2 more
core +1 more source
Enhancement of K+ conductance improves in vitro the contraction force of skeletal muscle in hypokalemic periodic paralysis [PDF]
An abnormal ratio between Na+ and K+ conductances seems to be the cause for the depolarization and paralysis of skeletal muscle in primary hypokalemic periodic paralysis.
Quasthoff, Stefan +7 more
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The enzymatic complex Nicotinamide Adenine Dinucleotide Phosphate (NADPH) oxidase (NOx) may be the principal source of reactive oxygen species (ROS). The NOX2 and NOX4 isoforms are tissue-dependent and are differentially expressed in slow-twitch fibers ...
Juliana Osório Alves +10 more
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Regulation of ClC-1 and KATP channels in action potential–firing fast-twitch muscle fibers [PDF]
Action potential (AP) excitation requires a transient dominance of depolarizing membrane currents over the repolarizing membrane currents that stabilize the resting membrane potential. Such stabilizing currents, in turn, depend on passive membrane conductance (Gm), which in skeletal muscle fibers covers membrane conductances for K+ (GK) and Cl− (GCl ...
Thomas Holm, Pedersen +4 more
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MiR-208b Regulates the Conversion of Skeletal Muscle Fiber Types by Inhibiting Mettl8 Expression
Skeletal muscle, the main source of animal meat products, contains muscle fiber as a key unit. It is well known that transformation takes place between different types of muscle fibers, however, the conversion mechanism is not clear. In a previous study,
Xiang Li +3 more
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