Results 61 to 70 of about 13,059 (220)

Integrated Proteomic and Metabolomic Analysis of Muscle Atrophy Induced by Hindlimb Unloading

Biomolecules
Skeletal muscle atrophy, which is induced by factors such as disuse, spaceflight, certain medications, neurological disorders, and malnutrition, is a global health issue that lacks effective treatment.
Yuan Wang, Xi Li, Na Li, Jiawei Du, Xiaodong Qin, Xiqing Sun, Yongchun Wang, Chengfei Li   +7 more
doaj   +1 more source

Muscle fiber-type specific terminal Schwann cell pathology leads to sprouting deficits following partial denervation in SOD1G93A mice

Neurobiology of Disease, 2020
Amyotrophic lateral sclerosis (ALS) is an adult-onset disease characterized by the progressive death of motoneurons and denervation of muscle fibers. To restore motor function, surviving motoneurons in partially denervated muscles typically sprout axons ...
Julia M. Harrison, Victor F. Rafuse
doaj   +1 more source

With Regard to the Expression Status of Sarcolemmal Aquaporin 4 in Human Muscular Dystrophies

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT Human muscular dystrophies are inherited muscle‐wasting diseases caused by the various kinds of gene mutations. Among them, Duchenne muscular dystrophy (DMD) is a representative type. Before the discovery of the causative dystrophin gene of DMD, the fragile myofiber plasma membrane was thought to be the trigger of myofiber necrosis in DMD ...
Yoshihiro Wakayama, Takahiro Jimi
wiley   +1 more source

In vitro and in vivo muscle mass and strength during the first week of critical illness

Intensive Care Medicine Experimental
Background Loss of muscle mass and strength is provoked by critical illness. Our primary aim was to study the development of muscle atrophy and weakness in vitro in isolated myofibers and in vivo muscle mass and in vitro muscle strength during the first ...
Wout J. Claassen, Isabel M. van Ruijven, Marloes van den Berg, Rianne J. Baelde, Alexcia Fortes Monteiro, Rajvi M. N. Balesar, Sylvia W. Hania, Donald L. van der Peet, Peter J. M. Weijs, Coen A. C. Ottenheijm, Sandra N. Stapel   +10 more
doaj   +1 more source

The ARK2N (C18ORF25) Genetic Variant Is Associated with Muscle Fiber Size and Strength Athlete Status

Metabolites
Background: Data on the genetic factors contributing to inter-individual variability in muscle fiber size are limited. Recent research has demonstrated that mice lacking the Arkadia (RNF111) N-terminal-like PKA signaling regulator 2N (Ark2n; also known ...
Rukiye Çığırtaş, Celal Bulgay, Hasan Hüseyin Kazan, Onur Akman, Goran Sporiš, George John, Rinat A. Yusupov, Rinat I. Sultanov, Andrey V. Zhelankin, Ekaterina A. Semenova, Andrey K. Larin, Nikolay A. Kulemin, Edward V. Generozov, Damir Jurko, Ildus I. Ahmetov   +14 more
doaj   +1 more source

Proteomic Profiling of Myofiber Repair Annexins and Their Role in Duchenne Muscular Dystrophy

PROTEOMICS, EarlyView.
ABSTRACT Myofiber regeneration and membrane repair play crucial roles in maintaining the continuous physiological functioning of the neuromuscular system. A swift and efficient repair mechanism enables the rapid restoration of sarcolemmal integrity following cellular impairment in damaged skeletal muscles.
Paul Dowling, Dounia Bouragba, Elisa Negroni, Capucine Trollet, Margit Zweyer, Dieter Swandulla, Kay Ohlendieck   +6 more
wiley   +1 more source

Re‐thinking peripheral dysfunctions in obesity: The emerging role of sulphaceutics and sulphanutraceutics

British Journal of Pharmacology, EarlyView.
Obesity is a chronic, relapsing, multisystem disease in which cardiometabolic risk arises from excess adiposity and progressive dysfunction of peripheral organs, ultimately disrupting endocrine and metabolic crosstalk among tissues. Within this network, sulphur‐based biology, centred on hydrogen sulphide and related reactive sulphur species, has ...
Martina Smimmo, Veronica Casale, Roberta d'Emmanuele di Villa Bianca, Valentina Vellecco, Mariarosaria Bucci   +4 more
wiley   +1 more source

Comparison of Phasic Store‐Operated Calcium Entry in Rat Slow‐ and Fast‐Twitch Muscle Fibers

Acta Physiologica
ABSTRACTAimThis study investigates the activation and regulation of phasic store‐operated calcium entry (pSOCE) in fast‐ and slow‐twitch skeletal muscle fibers. Specifically, we aimed to enhance the sensitivity of pSOCE detection in slow‐twitch fibers by optimizing ionic conditions and to compare the physiological relevance of pSOCE between fiber types.
Elena Lilliu, Rocky Choi, Karlheinz Hilber, Bradley Launikonis, Xaver Koenig   +4 more
openaire   +4 more sources

Electroacupuncture and category IV LASER for treating suprascapular neuropathy in a two‐year‐old Arabian filly

Equine Veterinary Education, EarlyView.
Summary A 2‐year‐old Arabian filly presented with acute onset grade 4/5 (AAEP) right forelimb lameness and hindlimb ataxia following a collision with another horse and subsequent fall. The right forelimb lameness was associated with marked scapulohumeral joint instability.
O. E. Newman, B. Dunkel, M. Perrier
wiley   +1 more source

Developmental characteristics of skeletal muscle in goose during the embryonic and early post-hatching periods

Poultry Science
Geese exhibit relatively low meat production and growth efficiency compared to broilers and ducks, with muscle fiber being key determinant of meat yield. The embryonic stage and early post-hatching period are critical for muscle fiber differentiation and
Kaiqi Weng, Yi Liu, Huiying Wang, Guohong Chen, Daqian He, Qi Xu   +5 more
doaj   +1 more source