Results 151 to 160 of about 86,308 (267)

Integrated effects of altered action potentials and calcium release on skeletal muscle force generation in transgenic Huntington's disease mice. [PDF]

open access: yesPflugers Arch
Miranda DR   +12 more
europepmc   +1 more source

Metformin enhances external urethral sphincter integrity and restores continence via AMPK activation in a rat model of stress urinary incontinence

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The pathogenesis of stress urinary incontinence (SUI) is intimately associated with injury to the external urethral sphincter (EUS). In this study, we established an SUI model induced by double vaginal distension and demonstrated that metformin treatment activated the AMPK signaling in the EUS tissue.
Yuting Xu   +7 more
wiley   +1 more source

A comprehensive proteome and phosphoproteome atlas across nine organs of the Chinese hamster

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study presents the first comprehensive proteome and phosphoproteome atlas of the Chinese hamster across nine organs (heart, liver, lung, kidney, spleen, cerebral cortex, skeletal muscle, stomach, and testis or ovary). A total of 14 219 proteins were identified in the proteome, with 11 828 phosphorylated proteins and 47 122 phosphorylation sites ...
Luyao Zhang   +15 more
wiley   +1 more source

Equine models in translational medicine: A comparative approach to human health

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh   +1 more
wiley   +1 more source

Location-Dependent Differences in Cardiac and Skeletal Muscle Dysfunction Associated With Truncating Titin (ttn.2) Variants. [PDF]

open access: yesCirc Res
Santiago CF   +14 more
europepmc   +1 more source

Muscle RING finger-1 facilitates skeletal muscle regeneration via regulating myoblast proliferation and differentiation. [PDF]

open access: yesJ Transl Med
Yang M   +10 more
europepmc   +1 more source

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