Role of PDK1 in skeletal muscle hypertrophy induced by mechanical load [PDF]
Phosphatidylinositol 3-kinase (PI3K) plays an important role in protein metabolism and cell growth. We here show that mice (M-PDK1KO mice) with skeletal muscle–specific deficiency of 3′-phosphoinositide–dependent kinase 1 (PDK1), a key component of PI3K ...
Naoki Kuramoto +6 more
doaj +2 more sources
Effect of spermidine intake on overload‐induced skeletal muscle hypertrophy in male mice [PDF]
Skeletal muscles exhibit high plasticity, such as overload‐induced hypertrophy or immobilization‐induced atrophy. During sports, skeletal muscle hypertrophy is induced by training to improve performance.
Tomohiro Iwata +4 more
doaj +2 more sources
miRNA‐1 regulation is necessary for mechanical overload‐induced muscle hypertrophy in male mice [PDF]
MicroRNAs (miRNAs) are small, noncoding RNAs that play a critical role in regulating gene expression post‐transcriptionally. They are involved in various developmental and physiological processes, and their dysregulation is linked to various diseases ...
Shengyi Fei +6 more
doaj +2 more sources
Triceps surae muscle hypertrophy is greater after standing versus seated calf-raise training [PDF]
Background: The triceps surae muscle plays important roles in fundamental human movements. However, this muscle is relatively unresponsive to resistance training (difficult to hypertrophy) but prone to atrophy with inactivity compared with other muscles.
Momoka Kinoshita +12 more
doaj +2 more sources
Chronic Effects of Static Stretching Exercises on Skeletal Muscle Hypertrophy in Healthy Individuals: A Systematic Review and Multilevel Meta-Analysis [PDF]
Background The chronic effect of static stretching (SS) on muscle hypertrophy is still unclear. This study aimed to examine the chronic effects of SS exercises on skeletal muscle hypertrophy in healthy individuals.
Fabian Arntz +7 more
doaj +2 more sources
Nutritional interventions in muscle hypertrophy research: a scientometric analysis within the context of resistance training (1992-2025). [PDF]
Chen W.
europepmc +3 more sources
Skeletal muscle is a plastic tissue that regenerates ad integrum after injury and adapts to raise mechanical loading/contractile activity by increasing its mass and/or myofiber size, a phenomenon commonly refers to as skeletal muscle hypertrophy.
Clara Bernard +4 more
doaj +1 more source
Effects of plyometric vs. resistance training on skeletal muscle hypertrophy: A review
Objective: In this review, we critically evaluate studies directly comparing the effects of plyometric vs. resistance training on skeletal muscle hypertrophy.
Jozo Grgic +2 more
doaj +1 more source
Maximizing the efficiency of resistance training
Introduction and objective: Resistance training is the main intervention that can develop an individual’s strength and muscle mass. When executed regularly, it provides significant health benefits.
Mateusz Pawlina +4 more
doaj +1 more source
There are a plethora of studies that have analyzed the effects of different resistance training methods on muscle hypertrophy. Recent studies have pointed out some potential advantage of training using cluster sets (CS) compared with traditional sets. It
Erick Carlos da Cunha Totó +5 more
doaj +1 more source

