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Resistance Training Recommendations to Maximize Muscle Hypertrophy in an Athletic Population: Position Stand of the IUSCA

open access: yesInternational Journal of Strength and Conditioning, 2021
Hypertrophy can be operationally defined as an increase in the axial cross-sectional area of a muscle fiber or whole muscle, and is due to increases in the size of pre-existing muscle fibers. Hypertrophy is a desired outcome in many sports.
Brad Schoenfeld   +7 more
doaj   +2 more sources

Effect of spermidine intake on overload‐induced skeletal muscle hypertrophy in male mice [PDF]

open access: yesPhysiological Reports
Skeletal muscles exhibit high plasticity, such as overload‐induced hypertrophy or immobilization‐induced atrophy. During sports, skeletal muscle hypertrophy is induced by training to improve performance.
Tomohiro Iwata   +4 more
doaj   +2 more sources

Recent advances in understanding resistance exercise training-induced skeletal muscle hypertrophy in humans [version 1; peer review: 2 approved]

open access: yesF1000Research, 2020
Skeletal muscle plays a pivotal role in the maintenance of physical and metabolic health and, critically, mobility. Accordingly, strategies focused on increasing the quality and quantity of skeletal muscle are relevant, and resistance exercise is ...
Sophie Joanisse   +5 more
doaj   +2 more sources

miRNA‐1 regulation is necessary for mechanical overload‐induced muscle hypertrophy in male mice [PDF]

open access: yesPhysiological Reports
MicroRNAs (miRNAs) are small, noncoding RNAs that play a critical role in regulating gene expression post‐transcriptionally. They are involved in various developmental and physiological processes, and their dysregulation is linked to various diseases ...
Shengyi Fei   +6 more
doaj   +2 more sources

Mechanisms of muscle atrophy and hypertrophy: implications in health and disease

open access: yesNature Communications, 2021
Skeletal muscle is the protein reservoir of our body and an important regulator of glucose and lipid homeostasis. Consequently, the growth or the loss of muscle mass can influence general metabolism, locomotion, eating and respiration.
Roberta Sartori   +2 more
exaly   +2 more sources

Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions.

open access: yesPhysiol Rev, 2023
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have been extensively researched since the landmark report by Morpurgo (1897) of "work-induced hypertrophy" in dogs that were treadmill-trained. Much of the pre-clinical rodent
Roberts MD   +13 more
europepmc   +2 more sources

Molecular Mechanisms of Skeletal Muscle Hypertrophy

open access: yesJournal of Neuromuscular Diseases, 2021
Skeletal muscle hypertrophy can be induced by hormones and growth factors acting directly as positive regulators of muscle growth or indirectly by neutralizing negative regulators, and by mechanical signals mediating the effect of resistance exercise. Muscle growth during hypertrophy is controlled at the translational level, through the stimulation of ...
Schiaffino S.   +3 more
openaire   +6 more sources

Triceps surae muscle hypertrophy is greater after standing versus seated calf-raise training [PDF]

open access: yesFrontiers in Physiology, 2023
Background: The triceps surae muscle plays important roles in fundamental human movements. However, this muscle is relatively unresponsive to resistance training (difficult to hypertrophy) but prone to atrophy with inactivity compared with other muscles.
Momoka Kinoshita   +12 more
doaj   +2 more sources

Requirement of myomaker-mediated stem cell fusion for skeletal muscle hypertrophy

open access: yeseLife, 2017
Fusion of skeletal muscle stem/progenitor cells is required for proper development and regeneration, however the significance of this process during adult muscle hypertrophy has not been explored.
Qingnian Goh, Douglas P Millay
doaj   +2 more sources

A Critical Evaluation of the Biological Construct Skeletal Muscle Hypertrophy: Size Matters but So Does the Measurement

open access: yesFrontiers in Physiology, 2019
Skeletal muscle is highly adaptable and has consistently been shown to morphologically respond to exercise training. Skeletal muscle growth during periods of resistance training has traditionally been referred to as skeletal muscle hypertrophy, and this ...
Cody T. Haun   +5 more
doaj   +2 more sources

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