Results 31 to 40 of about 5,764,466 (380)
Autophagy Is Required to Maintain Muscle Mass [PDF]
The ubiquitin-proteasome and autophagy-lysosome pathways are the two major routes for protein and organelle clearance. In skeletal muscle, both systems are under FoxO regulation and their excessive activation induces severe muscle loss. Although altered autophagy has been observed in various myopathies, the specific role of autophagy in skeletal muscle
E. MASIERO+9 more
openaire +3 more sources
Introduction Multiple domains of cognitive function decline with age, resulting in a significant burden on quality of life and the healthcare system. Recent studies increasingly point to links between muscle mass, particularly low muscle mass, and risk ...
Kristi L. Storoschuk+5 more
doaj +1 more source
. Background. It remains unclear about the association of muscle mass, strength, and quality with death in the general Chinese population of diverse economical and geographical backgrounds.
Man Wu+16 more
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Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease
Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh+5 more
wiley +1 more source
Aging modifies the body composition and physiology of individuals, influencing the decrease in body mass and nutritional status. This study aims to analyze the association between anthropometric indicators of muscle mass assessment with nutritional risk ...
Letícia Thalia Medim+6 more
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The dynamic coordination of processes controlling the quality of the mitochondrial network is crucial to maintain the function of mitochondria in skeletal muscle.
V. Romanello, M. Sandri
semanticscholar +1 more source
The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile
Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee+16 more
wiley +1 more source
Anthropometric parameters as predictors of muscle mass in elderly women
The aims of study were to analyze the relationship between muscle mass and anthropometric parameters in elderly women and to develop a mathematical model to predict muscle mass based on anthropometric parameters. The study included 63 elderly women (71.4
Fábio da Silva Santana+6 more
doaj +1 more source
PURPOSEAutologous hematopoietic stem cell transplantation (ASCT) has been introduced as a standard treatment for newly diagnosed multiple myeloma (NDMM) following novel agent-based induction chemotherapy.
Sung-Soo Park+7 more
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Going nuclear: Molecular adaptations to exercise mediated by myonuclei
Muscle fibers are multinucleated, and muscle fiber nuclei (myonuclei) are believed to be post-mitotic and are typically situated near the periphery of the myofiber.
Pieter J. Koopmans+2 more
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