Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
Are adult physiques geometrically similar? The dangers of allometric scaling using body mass power laws. [PDF]
Human physique classification by somatotype assumes that adult humans are geometric similar to each other. However, this assumption has yet to be adequately tested in athletic and nonexercising human populations.
Stewart, Arthur D. +7 more
core +1 more source
Cognitive Behavioral Therapy for Youth With Childhood‐Onset Lupus: A Randomized Clinical Trial
Objective Our objective was to determine the feasibility and acceptability of the Treatment and Education Approach for Childhood‐Onset Lupus (TEACH), a six‐session cognitive behavioral intervention addressing depressive, fatigue, and pain symptoms, delivered remotely to individual youth with lupus by a trained interventionist.
Natoshia R. Cunningham +29 more
wiley +1 more source
The thermal dependence of swimming and muscle physiology in temperate and Antarctic scallops
Swimming is important to the ecology of many species of scallop but the effects of temperature upon swimming are not clear. The ecology and natural history of scallops is introduced followed by a description of the state of current ...
Bailey, David Mark
core
Acute whole-body vibration elicits post-activation potentiation
Whole-body vibration (WBV) leads to a rapid increase in intra-muscular temperature and enhances muscle power. The power-enhancing eVects by WBV can, at least in part, be explained by intra-muscular temperature.
Stannard, Stephen R. +6 more
core +1 more source
Objective This study aimed to investigate potential moderators influencing the effects of manual therapy and exercise therapy on pain and functional outcomes in individuals with knee and/or hip osteoarthritis, using data from the MOA trial. This is a secondary analysis of data from the MOA trial that compares the clinical effectiveness of manual ...
Daniel Cury Ribeiro +2 more
wiley +1 more source
Simulation of surface EMG signals generated by muscle tissues with in-homogeneity due to fiber pinnation [PDF]
Surface electromyographic (EMG) signal modeling has important applications in the interpretation of experimental EMG data. Most models of surface EMG generation considered volume conductors homogeneous in the direction of propagation of the action ...
Farina, D., FARINA D., Mesin, Luca
core +1 more source
Effects of oxidation in the power of chemically skinned rat soleus fibres
Oxidation alters calcium sensitivity, and decreases maximum isometric force (Po) and shortening velocity (Vmax) of single muscle fibres. To examine the effect of oxidation on the curvature of the force-velocity relationship, which determines muscle power
Rittweger, Jörn +3 more
core
Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan +10 more
wiley +1 more source
Efecto del entrenamiento combinado de pliometría y electroestimulación en salto vertical. (Effect of combined plyometric and electrostimulation training on vertical jump).
Resumen En este estudio se han analizado los efectos del entrenamiento combinado de pliometría y electroestimulación en un entrenamiento de fuerza muscular de los miembros inferiores.
Elisa Benito Martínez +2 more
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