Results 181 to 190 of about 1,366,391 (310)

4D piezoceramic-integrated scaffolds with bioelectric cues for skeletal muscle regeneration. [PDF]

Bioact Mater
Ravaglia N, Rossi A, Vignolo M, Galizia P, Pacheco D, Arienti F, Baldisserri C, Guzzo CM, Montesi M, Mancinelli R, Labardi M, Patrício TMF, Glaum J, Cunha C, Mercadelli E, Luciano G, Panseri S.   +16 more
europepmc   +1 more source

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source

Nanoengineered GATA3⁺ Macrophages Transplantation Reconstitutes the Muscle Stem Cells Niche for Skeletal Muscle Regeneration. [PDF]

Int J Nanomedicine
Zhang P, Xu Y, Zhang Y, Yang J, Liu S, Yuan Y, Chen Y, Li C, Lu Y, Wang H, Liu J.   +10 more
europepmc   +1 more source

Modulating Calcium Homeostasis via a Biomimetic Scaffold to Rescue Diabetic Ischemic Wounds

Advanced Science, EarlyView.
This strategy addresses impaired microcirculation and loss of extracellular matrix (ECM) guidance in diabetic wound healing. Musc@CP, a nanofibrous dressing combining an ECM‐mimetic chitosan‐pullulan scaffold with muscone, enhances perfusion by attenuating intracellular Ca2+ overload‐associated endothelial dysfunction.
Xiang Zheng, Mingmei Li, Jianjun Jiang, Yongchao Wang, Yaru Jia, Weilun Sun, Yi Yao, Pengli Gao, Linhua Zhang, Qi Guo, Guang Jia, Xing‐Jie Liang, Dunwan Zhu, Jinchao Zhang, Fangzhou Li   +14 more
wiley   +1 more source

Beyond hormone deficiency: a framework for endocrine-immune-niche integration in aging skeletal muscle regeneration. [PDF]

Front Immunol
Perin L, Da Sacco S, Liu YY, Brent GA, Milanesi A.   +4 more
europepmc   +1 more source

ANGPTL4 Exacerbates Renal Injury in Diabetic Kidney Disease by Impairing Podocyte Lipophagy via Compromised Lysosomal Degradative Function

Advanced Science, EarlyView.
In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu, Shimin Jiang, Zhenkun Yang, Shunlai Shang, Jiayi Li, Guming Zou, Cheng Zhou, Wenge Li   +7 more
wiley   +1 more source

Dnajb5 From Antarctic Fish Reveals a Redox-Sensitive Mechanism Coordinating Muscle Regeneration via mTORC1 and HDAC4. [PDF]

J Cachexia Sarcopenia Muscle
Cho SH, Choi MK, Baek MO, Son HH, Nguyen BT, Kang MJ, Kim IC, Kim JH, Yoon MS.   +8 more
europepmc   +1 more source

YAP1‐Driven Pathogenic Fibro‐Adipogenic Progenitors Secrete IL‐6 and FGF21 to Mediate Muscle‐Bone Crosstalk and Promote Bone Loss

Advanced Science, EarlyView.
Fibro‐adipogenic progenitors (FAPs) in atrophic muscle undergo YAP1‐driven pathogenic activation, secreting IL‐6 and FGF21 as bone‐catabolic myokines that mediate muscle‐bone crosstalk and promote bone loss. Genetic or pharmacological targeting of this YAP1‐FAP‐myokine axis rescues skeletal deterioration, identifying FAP‐derived myokines as therapeutic
Xiaoyu Cai, Tao Xu, Rui Ma, Weikun Meng, Shutao Gao, Yakefu Abulizi, Alafate Kahaer, Chuanhui Xun, Maierdan Maimaiti, Rui Cao, Weidong Liang, Polati Maimaiti, Qiang Deng, Jun Sheng, Ting Wang, Mingchong Liu, Weibin Sheng   +16 more
wiley   +1 more source

Insights into the Roles of Aging and Chemokine Signaling During Neuromuscular Regeneration

Thesis (Ph.D.)--University of Rochester. School of Medicine & Dentistry. Dept. of Pharmacology and Physiology, 2023.Aging is associated with delayed skeletal muscle recovery from injury leading to increased morbidity in the elderly population ...
Furati, Esraa, Chakkalakal, Joe V.
core  

Efficacy of 810 nm low-level laser therapy on muscle regeneration after bupivacaine-induced myonecrosis in a rabbit model. [PDF]

Lasers Med Sci
Sadeldin MT, Hamadah O, Abdo A, Sayal L, Alnour A.   +4 more
europepmc   +1 more source