Results 221 to 230 of about 31,230 (296)

Three‐year outcomes of repeated botulinum neurotoxin A injections to the lower extremities in young children with spastic cerebral palsy in GMFCS levels I to III

Developmental Medicine &Child Neurology, Volume 68, Issue 6, Page 792-799, June 2026.
In this study, we followed a group of children 2 to 6 years old with spastic cerebral palsy functioning in GMFCS levels I–III, over 3 years. Sixty‐five received BoNT‐A and 59 did not. Repeated BoNT‐A injections over 3 years were not associated with improvements in gross motor function or passive ankle dorsiflexion. Daily step counts, favouring the BoNT‐
Darcy Fehlings, Emma Bohn, Lauren Switzer, Charles H. Goldsmith, Unni Narayanan, Peter L. Rosenbaum, F. Virginia Wright, Gary Foster, CP‐BoNT‐A Study Group, Timothy Carey, Mark Mason, Ronit Mesterman   +11 more
wiley   +1 more source

Advances in the diagnosis and management of post-stroke limb spasticity: a narrative review. [PDF]

Front Neurol
Su M, Yu M, Xu P, Fei Y.
europepmc   +1 more source

Tolerability, Safety and Effectiveness of Sigh Introduction During Non‐Invasive Mechanical Ventilation Cycles in Patients With Amyotrophic Lateral Sclerosis

European Journal of Neurology, Volume 33, Issue 6, June 2026.
In this randomized, proof‐of concept study, we assess the tolerability and effectiveness of adding a sigh cycle to non‐invasive mechanical ventilation (NIMV) settings in MND patients. Although the sigh was safe and well tolerated, no significant group differences were observed in the primary and secondary respiratory outcomes. Exploratory assessment of
Nilo Riva, Paride Schito, Tommaso Russo, Ottavia Eleonora Ferraro, Gianluca Durante, Andrea Tettamanti, Elisa Riboldi, Teuta Domi, Laura Pozzi, Angelo Quattrini, Mauro Comola, Federica Agosta, George Cremona, Massimo Filippi   +13 more
wiley   +1 more source

Development and preliminary validation of a multimodal instrument for spasticity quantification using a composite index: A pilot study. [PDF]

PLoS One
Rosero Ñañez JM, Schaly S, Gonzalez ER, Urbano Díaz MLÁ, Villamarín Muñoz JA.   +4 more
europepmc   +1 more source

The Long Haul: Microtubule Motors as the Essential Supply Line for Neuronal Longevity

Journal of Neurochemistry, Volume 170, Issue 6, June 2026.
To survive a lifetime, neurons depend on a high‐fidelity logistics network powered by microtubule motors. We explore how a broad spectrum of genetic defects in this machinery drive a devastating spectrum of neurodevelopmental and neurodegenerative diseases, including Hereditary Spastic Paraplegia (HSP), Charcot–Marie‐Tooth Type 2 (CMT2), and ...
Emma D. Turner, Alison E. Twelvetrees
wiley   +1 more source

Intrathecal Baclofen in Children with Cerebral Palsy: A Critical Review of Selection Criteria, Rehabilitation Goals, Outcomes, and Complications. [PDF]

J Clin Med
Retkowska-Tomaszewska N, Defort P, Barciszewska AM, Patkowski D.   +3 more
europepmc   +1 more source

Biallelic Nonsense Variants in NEFL May Cause a Non‐Length‐Dependent Neuropathy With Temporal Dispersion on Nerve Conduction Studies

Journal of the Peripheral Nervous System, Volume 31, Issue 2, June 2026.
ABSTRACT Background and Aims Pathogenic variants in NEFL, the gene that encodes the light polypeptide subunit of neurofilaments, are an uncommon cause of autosomal recessive Charcot‐Marie‐Tooth (CMT) disease. In this study, we describe the clinical and electrophysiological features of two families with early‐onset CMT carrying nonsense variants in the ...
Marcus Vinícius Vieira da Silva Gomes, Pedro José Tomaselli, Wilson Marques Jr   +2 more
wiley   +1 more source

Stretching-Positioned Extracorporeal Shock Wave Therapy Yields Superior Short-Term Efficacy for Post-Stroke Upper-Limb Spasticity: A Retrospective Comparative Study. [PDF]

Med Sci Monit
Ouyang J, Xu J, Li C, Li Y, Liao Z, Song H.   +5 more
europepmc   +1 more source

COQ7‐Related Neuropathy: Two New Cases and Review of the Literature

Journal of the Peripheral Nervous System, Volume 31, Issue 2, June 2026.
ABSTRACT Background and Aims Biallelic variants in COQ7 have been associated with inherited neuropathy. COQ7 encodes a mitochondrial protein directly involved in coenzyme Q10 (CoQ10) biosynthesis. Methods Two unreported and unrelated cases of COQ7‐related neuropathy are presented, along with a review of all previously published cases to highlight the ...
Julian Theuriet, Shams Ribault, Fanny Fontaine, Naïg Gueguen, Arnaud Jacquier, Isabelle Quadrio, Zoe Dmitrievsky, Marina Konyukh, Dominique Bonneau, Stéphane Allouche, Julien Cassereau, Christophe Verny, Virginie Guillet‐Pichon, Antoine Pegat   +13 more
wiley   +1 more source