Results 81 to 90 of about 51,598 (348)

Effects of neuromuscular electrical stimulation on gait performance in chronic stroke with inadequate ankle control - A randomized controlled trial.

PLoS ONE, 2018
Neuromuscular electrical stimulation (NMES) has been used to improve muscle strength and decrease spasticity of the ankle joint in stroke patients.
Yea-Ru Yang, Pei-Ling Mi, Shih-Fong Huang, Shiu-Ling Chiu, Yan-Ci Liu, Ray-Yau Wang   +5 more
doaj   +1 more source

Non-invasive treatment of patients with upper extremity spasticity following stroke using paired trans-spinal and peripheral direct current stimulation

Bioelectronic Medicine, 2019
Background Muscle spasticity is a common impediment to motor recovery in patients with chronic stroke. Standard-of-care treatments such as botulinum toxin injections can temporarily relieve muscle stiffness and pain associated with spasticity, but often ...
Alexandra Paget-Blanc, Johanna L. Chang, Maira Saul, Regina Lin, Zaghloul Ahmed, Bruce T. Volpe   +5 more
doaj   +1 more source

Infantile‐Onset Ascending Hereditary Spastic Paraplegia due to a Homozygous ALS2 Exons 24–25 Deletion: Expanding the Genotypic Spectrum

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT We describe a novel homozygous intragenic deletion in the ALS2 gene in an 8‐year‐old boy with Infantile‐onset Ascending Hereditary Spastic Paraplegia (IAHSP) and oculomotor apraxia, thereby contributing to the expanding genetic landscape of ALS2‐related disorders.
Vito Luigi Colona, Maria Gnazzo, Silvia Genovese, Gessica Vasco, Lorena Travaglini, Maurizio Sabbadini, Marina Macchiaiolo, Francesco Nicita, Jacopo Sartorelli, Carmelo Piscopo, Enrico Castelli, Enrico Bertini, Andrea Bartuli, Antonio Novelli, Gessica Della Bella, Davide Vecchio   +15 more
wiley   +1 more source

The spasticity in the motor and functional disability in adults with post-stroke hemiparetic

Fisioterapia em Movimento
Introduction: Spasticity acts as a limiting factor in motor and functional recovery after Stroke, impairing the performance of daily living activities.
Roberta de Oliveira Cacho, Enio Walker Azevedo Cacho, Anderson Barbosa Loureiro, Gabriele Natane de Medeiros Cirne, Silvana Alves Pereira, Rodrigo Pegado de Abreu Freitas, Núbia Maria Freire Vieira Lima, Guilherme Borges   +7 more
doaj   +1 more source

Modulation of Stretch Reflexes of the Finger Flexors by Sensory Feedback from the Proximal Upper Limb Poststroke [PDF]

, 2006
Neural coupling of proximal and distal upper limb segments may have functional implications in the recovery of hemiparesis after stroke. The goal of the present study was to investigate whether the stretch reflex response magnitude of spastic finger ...
Hoffmann, Gilles, Kahn, Jennifer H., Kamper, Derek G., Rymer, WIlliam Zev, Schmit, Brian D.   +4 more
core   +1 more source

Stepping Responses to Treadmill Perturbations vary with Severity of Motor Deficits in Human SCI [PDF]

, 2018
In this study, we investigated the responses to tread perturbations during human stepping on a treadmill. Our approach was to test the effects of perturbations to a single leg using a split-belt treadmill in healthy participants and in participants with ...
Chu, Virginia W. T., Hornby, T. George, Schmit, Brian   +2 more
core   +2 more sources

Cuneiform Nucleus Stimulation Can Assist Gait Training to Promote Locomotor Recovery in Individuals With Incomplete Tetraplegia

Annals of Neurology, EarlyView.
Objective Impaired ability to induce stepping after incomplete spinal cord injury (SCI) can limit the efficacy of locomotor training, often leaving patients wheelchair‐bound. The cuneiform nucleus (CNF), a key mesencephalic locomotor control center, modulates the activity of spinal locomotor centers via the reticulospinal tract.
Anna‐Sophie Hofer, Lennart H. Stieglitz, Marc Bolliger, Linard Filli, Adrian Cathomen, Romina Willi, Irina Lerch, Iris Krüsi, Melina Giagiozis, Christian Meyer, Martin Schubert, Michèle Hubli, Thomas M. Kessler, László Demkó, Christian R. Baumann, Lukas Imbach, Markus F. Oertel, Andrea Prusse, Alina Kiseleva, Luca Regli, Martin E. Schwab, Armin Curt   +21 more
wiley   +1 more source

Botulinum toxin treatment of spasticity in diplegic cerebral palsy : a randomised, double-blind, placebo-controlled, dose-ranging study [PDF]

This study evaluated the efficacy and safety of three doses of botulinum toxin A (BTX-A; Dysport®) in 125 patients (mean age 5.2 years, SD 2; 54% male)with dynamic equinus spasticity during walking. Participants were randomized to receive Dysport (10,
Bakheit, Boyd, Calderon-Gonzalez, Carr, Chutorian, Corry, Corry, Corry, Cosgrove, Denislic, Eames, Flett, Friedman, Haley, Heinen, Heinen, Hesse, Holly, Koman, Koman, Koman, Mall, Mousny, Msall, Russell, Russell, Sanchez-Carpintero, Scott, Sutherland, US Food and Drug Administration, Center for Drug Evaluation and Research, Wissel, World Health Organization., Yang   +32 more
core   +1 more source

Effect of Tendon Vibration on Hemiparetic Arm Stability in Unstable Workspaces [PDF]

, 2015
Sensory stimulation of wrist musculature can enhance stability in the proximal arm and may be a useful therapy aimed at improving arm control post-stroke.
Conrad, Megan O., Gadhoke, Bani, Scheidt, Robert A., Schmit, Brian D.   +3 more
core   +4 more sources

Non‐Synaptic Function and Localization of Syntaxin‐Binding Protein 1 in a Mouse Model of STXBP1‐Related Epileptic Encephalopathy

Annals of Neurology, EarlyView.
Objective De novo mutations in the syntaxin‐binding protein 1 (STXBP1), encoded by STXBP1, are among the most prevalent causes of variable neurodevelopmental disorders, including epileptic encephalopathy, developmental delay, and movement disorders.
Tao Yang, Rajat Banerjee, Yamei Deng, Sheetal Jahagirdar1, Alexey I. Nesvizhskii, Michael D. Uhler, Jack M. Parent, Yu Wang   +7 more
wiley   +1 more source