Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng +6 more
wiley +1 more source
The relationship between muscle sympathetic nerve activity and systemic hemodynamics is altered in women with uterine fibroids. [PDF]
Harvey RE +6 more
europepmc +1 more source
Schematic representation of the shared pathophysiological mechanisms underlying heart failure (HF) and atrial fibrillation (AF), including inflammation, oxidative stress, endothelial dysfunction, and fibrosis. The figure highlights the clinical and mechanistic convergence of conventional pharmacological therapies and selected nutraceuticals in ...
Laura Beatrice Mattioli +6 more
wiley +1 more source
Stimulation of the dorsolateral prefrontal cortex modulates muscle sympathetic nerve activity and blood pressure in humans. [PDF]
Sesa-Ashton G +6 more
europepmc +1 more source
Sympathetic Nerve Activity in Monozygotic Twins
Microneurographic recordings of human muscle sympathetic nerve activity responses to sudden sensory stimuli (ie, arousal) have revealed 2 intraindividually reproducible response profiles in healthy young males that predict different neural ...
Mikael Elam +9 more
core +1 more source
A 3D‐bioprinted platform with stem cells activates “nerve‐bone” signaling by enabling the spatiotemporal delivery of Nell‐1. This activation enhances neurovascular and bone regeneration through the CYFIP1 cascade. In rat calvarial defects, the platform doubled bone regeneration and nerve repair and tripled vascular density, resulting in superior ...
Minjia Zhu +11 more
wiley +1 more source
Effect of adaptive servo-ventilation for central sleep apnoea in systolic heart failure on muscle sympathetic nerve activity: a SERVE-HF randomised ancillary study. [PDF]
Tamisier R +9 more
europepmc +1 more source
Evaluation of systemic consequences of brachycephalic obstructive airway syndrome in dogs
Abstract Background Brachycephalic obstructive airway syndrome (BOAS) results from upper airway anatomical abnormalities and may cause systemic effects depending on severity. Methods A prospective, case‒control and observational study was conducted.
Andréia Coutinho Facin +11 more
wiley +1 more source
Brain structural and functional correlates to defense-related inhibition of muscle sympathetic nerve activity in man. [PDF]
Riaz B +9 more
europepmc +1 more source
Implications of a local overproduction of tumor necrosis factor-α in complex regional pain syndrome [PDF]
Objective. To review the implications of a local overproduction of tumor necrosis factor-α for the pathogenesis and treatment of complex regional pain syndrome. Background.
Walker, S., Drummond, P.D.
core

