Results 51 to 60 of about 928,159 (244)

External walking environment differentially affects muscle synergies in children with cerebral palsy and typical development

open access: yesFrontiers in Human Neuroscience, 2022
Despite external environmental changes in walking, such as manipulating gait speed, previous studies have shown that the underlying muscle synergy structures (synergy weights or vectors) rarely vary.
Yushin Kim   +2 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Sequential Auctions with Synergies: The Paradox of Positive Synergies. [PDF]

open access: yes
In multi-unit (procurement) auctions winning multiple contracts can lead to cost advantages due to synergies. As an example one can think of procurement auctions where construction firms have returns to scale for investments in specialized equipments and
Vermeulen, Dries   +2 more
core   +2 more sources

Intra-Subject Consistency during Locomotion: Similarity in Shared and Subject-Specific Muscle Synergies

open access: yesFrontiers in Human Neuroscience, 2017
Human locomotion is a complex motor task. Previous research hypothesized that muscle synergies reflect the modular control of muscle groups operated by the Central Nervous System (CNS).
Daniele Rimini   +2 more
doaj   +1 more source

Greater Reliance on Cerebral Palsy-Specific Muscle Synergies During Gait Relates to Poorer Temporal-Spatial Performance Measures

open access: yesFrontiers in Physiology, 2021
Children with cerebral palsy typically exhibit reduced complexity of muscle coordination patterns during walking; however, the specific patterns that characterize their gait abnormalities are still not well documented.
Yushin Kim   +2 more
doaj   +1 more source

Changes in Immune‐Inflammation Status and Prognosis in Pregnancy‐Related Cerebral Venous Thrombosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Distinguishing pathological changes from physiological adaptations in pregnancy‐related cerebral venous thrombosis (CVT) is clinically challenging. This study aimed to characterize coagulation, immune‐inflammation, and dehydration status in these patients and assess their prognostic value.
Xiaoming Zhang   +7 more
wiley   +1 more source

Lower Local Dynamic Stability and Invariable Orbital Stability in the Activation of Muscle Synergies in Response to Accelerated Walking Speeds

open access: yesFrontiers in Human Neuroscience, 2018
In order to achieve flexible and smooth walking, we must accomplish subtasks (e. g., loading response, forward propulsion or swing initiation) within a gait cycle.
Benio Kibushi   +5 more
doaj   +1 more source

Advances in Sustainable and Wearable Textile Based Soft Robotics

open access: yesAdvanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas   +6 more
wiley   +1 more source

Mechanical muscle properties and intermuscular coordination in maximal and submaximal cycling: theoretical and practical implications [PDF]

open access: yes, 2014
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel UniversityThe ability of an individual to perform a functional movement is determined by a range of mechanical properties including the force and power producing ...
Barratt, Paul
core   +6 more sources

Biodegradable and Biocompatible Functional Polymers for Biomedical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Biodegradable and biocompatible functional polymers integrate electrical, mechanical, and stimuli‐responsive functionalities while enabling programmed degradation under physiological conditions. This review introduces recent advances in conductive, shape‐memory, self‐healing, photocurable, and adhesive polymer systems, emphasizing material design ...
Won Bae Han   +5 more
wiley   +1 more source

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