Results 61 to 70 of about 23,644 (300)
On Neuromechanical Approaches for the Study of Biological Grasp and Manipulation
, 2017 Biological and robotic grasp and manipulation are undeniably similar at the level of mechanical task performance. However, their underlying fundamental biological vs.
Santello, Marco +1 more
core +1 more source
Control of reaching movements by muscle synergy combinations [PDF]
, 2013 Controlling the movement of the arm to achieve a goal, such as reaching for an object, is challenging because it requires coordinating many muscles acting on many joints. The central nervous system (CNS) might simplify the control of reaching by directly
d'Avella, A, Lacquaniti, F
core +1 more source
The case for and against muscle synergies [PDF]
Current Opinion in Neurobiology, 2009 A long standing goal in motor control is to determine the fundamental output controlled by the CNS: does the CNS control the activation of individual motor units, individual muscles, groups of muscles, kinematic or dynamic features of movement, or does it simply care about accomplishing a task?
Matthew C, Tresch, Anthony, Jarc
openaire +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Frontiers in Bioengineering and Biotechnology, 2015 Investigation of neural representation of movement planning has attracted the attention of neuroscientists, as it may reveal the sensorimotor transformation essential to motor control.
Hiroaki eHirai +13 more
doaj +1 more source
Muscle Synergies in Children Walking and Running on a Treadmill
Frontiers in Human Neuroscience, 2021 Muscle synergies reflect the presence of a common neural input to multiple muscles. Steering small sets of synergies is commonly believed to simplify the control of complex motor tasks like walking and running. When these locomotor patterns emerge, it is
Margit M. Bach +2 more
doaj +1 more source
Do muscle synergies reduce the dimensionality of behavior? [PDF]
, 2014 The muscle synergy hypothesis is an archetype of the notion of Dimensionality Reduction (DR) occurring in the central nervous system due to modular organisation.
Harris, CM, Kuppuswamy, N
core +3 more sources
DO MUSCLE SYNERGIES ACTUALLY WORK? [PDF]
Journal of Experimental Biology, 2009 ![Figure][1] Animals have a lot of muscles, and many of them do similar things. To an engineer, the multitude of muscles poses a conundrum. When a frog wants to kick its leg back, extending its hip, it could use either the gracilis muscle or the semimembranosus.
openaire +1 more source
Robustness of muscle synergies during visuomotor adaptation [PDF]
Frontiers in Computational Neuroscience, 2013 During visuomotor adaptation a novel mapping between visual targets and motor commands is gradually acquired. How muscle activation patterns are affected by this process is an open question. We tested whether the structure of muscle synergies is preserved during adaptation to a visuomotor rotation.
Gentner, Reinhard +3 more
openaire +4 more sources
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source