Results 51 to 60 of about 489,532 (305)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

The Invalidity of the Laplace Law for Biological Vessels and of Estimating Elastic Modulus from Total Stress vs. Strain: a New Practical Method [PDF]

, 2013
The quantification of the stiffness of tubular biological structures is often obtained, both in vivo and in vitro, as the slope of total transmural hoop stress plotted against hoop strain. Total hoop stress is typically estimated using the "Laplace law."
Brasseur, James G., Costanzo, Francesco
core   +1 more source

Through Thick and Thin—Interfilament Communication in Muscle [PDF]

Biophysical Journal, 2015
Muscles contract via interaction between thick (myosin-containing) and thin (actin-containing) filaments in response to increased levels of calcium. During contraction, the myosin heads extend from the thick filament surface and attach to actin in the thin filaments, causing the filaments to slide past each other in a cyclic, ATP-driven process ...
Woodhead, John L., Craig, Roger
openaire   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Microstructural analysis of skeletal muscle force generation during aging. [PDF]

, 2020
Human aging results in a progressive decline in the active force generation capability of skeletal muscle. While many factors related to the changes of morphological and structural properties in muscle fibers and the extracellular matrix (ECM) have been ...
Basava, Ramya R, Chen, Jiun-Shyan, He, Qizhi, He, Xiaolong, Hodgson, John, Sinha, Shantanu, Sinha, Usha, Zhang, Yantao   +7 more
core   +1 more source

Effects of Whole Body Electromyostimulation on Muscle Activity and Muscle Thickness of Rectus Femoris, and Muscle Thickness of Abdominis Muscle in Healthy Adults

Physical Therapy Korea, 2019
Background: Whole body-electromyostimulation (WB-EMS) is widely used for the rehabilitation and recovery of patients with various neuromusculoskeletal disorders.Objects: To objectively measure changes in lower extremity and abdominal muscles after sit-to-stand dynamic movement training using WB-EMS.Methods: A total of 46 healthy adults (23 experimental
Keun-hyo Lee, Se-jin Park, Seung-chul Chon   +2 more
openaire   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Assessment of Masseter Muscle Hardness by Ultrasound Elastography and Hardness Meter in Healthy Individuals – An Observational Study

National Journal of Clinical Anatomy
Background: Examining the masseter muscle is crucial in assessment of temporomandibular disorders, hypertrophy, and sports injuries. The study aims to assess the hardness of masseter muscle in normal adults by muscle hardness meter and ultrasound ...
Deepa Jatti Patil, Rajesh Kumar Rathore, Ashutosh Patel   +2 more
doaj   +1 more source

Relationships between lower-body muscle structure and, lower-body strength, explosiveness and eccentric leg stiffness in adolescent athletes [PDF]

, 2015
The purpose of the present study was to determine whether any relationships were present between lower-body muscle structure and, lower-body strength, variables measured during a counter-movement jump (CMJ) and squat jump (SJ), and eccentric leg ...
Farley, Oliver R, Lundgren, Lina, Nimphius, Sophia, Secombe, Josh L., Sheppard, Jeremy M, Tran, Tai T.   +5 more
core   +1 more source