Results 91 to 100 of about 115,632 (206)

Effects of resveratrol on cancer cachexia in a mouse model [PDF]

, 2011
Cancer cachexia, characterized by muscle wasting and fatigue, affects many cancer patients. Inflammatory processes are implicated in the pathobiology of cancer cachexia.
Mansfield, Jessica
core  

Single cell analysis reveals the involvement of the long non-coding RNA Pvt1 in the modulation of muscle atrophy and mitochondrial network [PDF]

, 2019
Long non-coding RNAs (lncRNAs) are emerging as important players in the regulation of several aspects of cellular biology. For a better comprehension of their function, it is fundamental to determine their tissue or cell specificity and to identify their
Alessio, Enrico, Bertoli, Alessandro, Buson, Lisa, Cagnin, Stefano, Chemello, Francesco, Grespi, Francesca, Lanfranchi, Gerolamo, Martini, Paolo, Massimino, Maria L, Millino, Caterina, Pacchioni, Beniamina, Peggion, Caterina, Romualdi, Chiara, Scorrano, Luca   +13 more
core   +1 more source

Grape seed extract prevents skeletal muscle wasting in interleukin 10 knockout mice [PDF]

, 2014
BACKGROUND: Muscle wasting is frequently a result of cancers, AIDS, chronic diseases and aging, which often links to muscle inflammation. Although grape seed extract (GSE) has been widely used as a human dietary supplement for health promotion and ...
Bo Wang, Guan Yang, Meijun Zhu, Min Du, Xingwei Liang   +4 more
core   +2 more sources

Utility and safety of tocilizumab in Takayasu arteritis with severe heart failure and muscle wasting

ESC Heart Failure, 2019
Takayasu arteritis (TA) is a large vessel vasculitis of unknown aetiology characterized by chronic inflammatory changes of the aorta and its major branches.
Toshiyuki Yano, Arata Osanami, Masaki Shimizu, Satoshi Katano, Nobutaka Nagano, Hidemichi Kouzu, Masayuki Koyama, Atsuko Muranaka, Ryo Harada, Hirosato Doi, Nobuyoshi Kawaharada, Tetsuji Miura   +11 more
doaj   +1 more source

Nuclear magnetic resonance in conjunction with functional genomics suggests mitochondrial dysfunction in a murine model of cancer cachexia

, 2013
Cancer patients commonly suffer from cachexia, a syndrome in which tumors induce metabolic changes in the host that lead to massive loss in skeletal muscle mass.
Argilés Huguet, Josep Ma., Busquets Rius, Sílvia, Constantinou, Caterina, Fontes de Oliveira, Cibely Cristine, He, Jianxin, Kesarwani, Meenu, Mindrinos, Michael, Mintzopoulos, Dionyssios, Rahme, Laurence G., Tzika, A. Aria   +9 more
core   +1 more source

Triclosan exposure exacerbates muscle wasting via senescence and IGF-1 pathway suppression: A combined epidemiological and experimental study

Ecotoxicology and Environmental Safety
Triclosan, a broad-spectrum bactericide in various consumer products, has become a ubiquitous environmental contaminant, with detectable residues found in aquatic systems and human urine.
Zhenlin Yang, Liangshi Hao, Amila Kuati, Xiang Wang, Ziling Qian, Changning Hao, Junli Duan, Boshen Yang, Yuankang Zhu   +8 more
doaj   +1 more source

Determining the role of tumor-derived leukemia inhibitory factor in cancer cachexia using a genetic approach [PDF]

, 2018
Cachexia is a multifactorial metabolic wasting syndrome that affects a large percentage of cancer patients and results in the involuntary loss of skeletal muscle and adipose tissue.
Ganey, John
core  

Cardiac cachexia and muscle wasting: definition, physiopathology, and clinical consequences

Research Reports in Clinical Cardiology, 2014
Marina P Okoshi,1 Fernando G Romeiro,1 Paula F Martinez,1,2 Silvio A Oliveira Jr,1,2 Bertha F Polegato,1 Katashi Okoshi11Internal Medicine Department, Botucatu Medical School, Sao Paulo State University, UNESP, Sao Paulo, Brazil; 2School of Physiotherapy,
Okoshi MP, Romeiro FG, Martinez PF, Oliveira Jr SA, Polegato BF, Okoshi K   +5 more
doaj  

Longitudinal RNA-Seq analysis of acute and chronic neurogenic skeletal muscle atrophy. [PDF]

, 2019
Skeletal muscle is a highly adaptable tissue capable of changes in size, contractility, and metabolism according to functional demands. Atrophy is a decline in mass and strength caused by pathologic loss of myofibrillar proteins, and can result from ...
Coppola, Giovanni, Ehmsen, Jeffrey T, Höke, Ahmet, Kawaguchi, Riki, Mi, Ruifa   +4 more
core  

Mechanisms of muscle wasting in sarcopenia.

Revista brasileira de reumatologia, 2012
Approximately 66% of the patients with rheumatoid arthritis (RA) have signifi cant loss of cell mass (rheumatoid cachexia), mainly of skeletal muscle (rheumatoid sarcopenia). Sarcopenia is defi ned as muscle wasting associated with functional impairment.
Teixeira, Vivian de Oliveira Nunes, Filippin, Lidiane Isabel, Xavier, Ricardo Machado   +2 more
openaire   +2 more sources