Results 151 to 160 of about 115,632 (206)
Low fT3/fT4 ratio as a proxy for muscle wasting in patients with advanced non-small cell lung cancer treated with pembrolizumab. [PDF]
Eccher S +19 more
europepmc +1 more source
Ghrelin ameliorates sepsis-induced acute skeletal muscle wasting via hypothalamic JAK2/STAT3-AgRP pathway. [PDF]
Duan K +8 more
europepmc +1 more source
Disease entity impacts muscle wasting in the ICU with COVID-19 patients losing muscle nearly twice as fast. [PDF]
Kolck J +6 more
europepmc +1 more source
Activated Microglia Mediate the Motor Neuron-, Synaptic Denervation- and Muscle Wasting-Changes in Burn Injured Mice. [PDF]
Chen J +7 more
europepmc +1 more source
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Current Opinion in Clinical Nutrition and Metabolic Care, 2015
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Attaix, Didier +2 more
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Attaix, Didier +2 more
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The International Journal of Biochemistry & Cell Biology, 2013
Skeletal muscle loss appears to be the most significant clinical event in cancer cachexia and is associated with a poor outcome. With regard to such muscle loss, despite extensive study in a range of models, there is ongoing debate as to whether a reduction in protein synthesis, an increase in degradation or a combination of both is the more relevant ...
N, Johns, N A, Stephens, K C H, Fearon
openaire +2 more sources
Skeletal muscle loss appears to be the most significant clinical event in cancer cachexia and is associated with a poor outcome. With regard to such muscle loss, despite extensive study in a range of models, there is ongoing debate as to whether a reduction in protein synthesis, an increase in degradation or a combination of both is the more relevant ...
N, Johns, N A, Stephens, K C H, Fearon
openaire +2 more sources
Clinical Science, 1988
1. We have investigated arteriovenous exchanges of tyrosine and 3-methylhistidine across leg tissue in the postabsorptive state as specific indicators of net protein balance and myofibrillar protein breakdown, respectively, in eight patients with emphysema and in 11 healthy controls. Whole-body protein turnover was measured using l-[1-13C]leucine.
W L, Morrison +3 more
openaire +2 more sources
1. We have investigated arteriovenous exchanges of tyrosine and 3-methylhistidine across leg tissue in the postabsorptive state as specific indicators of net protein balance and myofibrillar protein breakdown, respectively, in eight patients with emphysema and in 11 healthy controls. Whole-body protein turnover was measured using l-[1-13C]leucine.
W L, Morrison +3 more
openaire +2 more sources
The International Journal of Biochemistry & Cell Biology, 2005
Calpains are intracellular nonlysosomal Ca(2+)-regulated cysteine proteases. They mediate regulatory cleavages of specific substrates in a large number of processes during the differentiation, life and death of the cell. The purpose of this review is to synthesize our current understanding of the participation of calpains in muscle atrophy.
Bartoli, Marc, Richard, I
openaire +3 more sources
Calpains are intracellular nonlysosomal Ca(2+)-regulated cysteine proteases. They mediate regulatory cleavages of specific substrates in a large number of processes during the differentiation, life and death of the cell. The purpose of this review is to synthesize our current understanding of the participation of calpains in muscle atrophy.
Bartoli, Marc, Richard, I
openaire +3 more sources

