Results 201 to 210 of about 55,731 (254)
The TWEAK/Fn14 signaling mediates skeletal muscle wasting during cancer cachexia. [PDF]
iScienceTomaz da Silva M +8 more
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Puerarin-loaded injectable hydrogel mitigates skeletal muscle wasting in colorectal cancer cachexia by targeting inflammatory signaling and improving protein homeostasis. [PDF]
Mater Today BioLi R +7 more
europepmc +1 more source
Nuciferine Attenuates Cancer Cachexia-Induced Muscle Wasting in Mice via HSP90AA1. [PDF]
J Cachexia Sarcopenia MuscleAn X +9 more
europepmc +1 more source
The gut-muscle axis: a comprehensive review of the interplay between physical activity and gut microbiota in the prevention and treatment of muscle wasting disorders. [PDF]
Front MicrobiolXu Y, He B.
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Current Opinion in Clinical Nutrition and Metabolic Care, 2015
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Attaix, Didier +2 more
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Attaix, Didier +2 more
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The International Journal of Biochemistry & Cell Biology, 2005
Calpains are intracellular nonlysosomal Ca(2+)-regulated cysteine proteases. They mediate regulatory cleavages of specific substrates in a large number of processes during the differentiation, life and death of the cell. The purpose of this review is to synthesize our current understanding of the participation of calpains in muscle atrophy.
Bartoli, Marc, Richard, I
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Calpains are intracellular nonlysosomal Ca(2+)-regulated cysteine proteases. They mediate regulatory cleavages of specific substrates in a large number of processes during the differentiation, life and death of the cell. The purpose of this review is to synthesize our current understanding of the participation of calpains in muscle atrophy.
Bartoli, Marc, Richard, I
openaire +3 more sources
The International Journal of Biochemistry & Cell Biology, 2013
Skeletal muscle loss appears to be the most significant clinical event in cancer cachexia and is associated with a poor outcome. With regard to such muscle loss, despite extensive study in a range of models, there is ongoing debate as to whether a reduction in protein synthesis, an increase in degradation or a combination of both is the more relevant ...
N, Johns, N A, Stephens, K C H, Fearon
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Skeletal muscle loss appears to be the most significant clinical event in cancer cachexia and is associated with a poor outcome. With regard to such muscle loss, despite extensive study in a range of models, there is ongoing debate as to whether a reduction in protein synthesis, an increase in degradation or a combination of both is the more relevant ...
N, Johns, N A, Stephens, K C H, Fearon
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Clinical Science, 1988
1. We have investigated arteriovenous exchanges of tyrosine and 3-methylhistidine across leg tissue in the postabsorptive state as specific indicators of net protein balance and myofibrillar protein breakdown, respectively, in eight patients with emphysema and in 11 healthy controls. Whole-body protein turnover was measured using l-[1-13C]leucine.
W L, Morrison +3 more
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1. We have investigated arteriovenous exchanges of tyrosine and 3-methylhistidine across leg tissue in the postabsorptive state as specific indicators of net protein balance and myofibrillar protein breakdown, respectively, in eight patients with emphysema and in 11 healthy controls. Whole-body protein turnover was measured using l-[1-13C]leucine.
W L, Morrison +3 more
openaire +2 more sources
Orthopaedic Nursing, 2003
The loss of lean body mass (muscle wasting) is initiated by cascades or events that precipitate increased proteolysis. Muscle wasting is stimulated by internal and external factors. Humorally related feedback loops stimulated by disease states, e.g., cancer, inflammatory myopathies, leukemia, or sepsis, and initiated as a response to systemic ...
openaire +2 more sources
The loss of lean body mass (muscle wasting) is initiated by cascades or events that precipitate increased proteolysis. Muscle wasting is stimulated by internal and external factors. Humorally related feedback loops stimulated by disease states, e.g., cancer, inflammatory myopathies, leukemia, or sepsis, and initiated as a response to systemic ...
openaire +2 more sources