Results 191 to 200 of about 945,377 (287)

Glucocorticoid Receptor Signaling in Myeloid Cells Orchestrates Inflammation Resolution and Muscle Repair

Advanced Science, EarlyView.
Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo, Joe G. Rizk, Emilia Calvano, Rajesh Sahu, Emina Colovic, Imane Chabba, Valentine Gilbart, Erwan Grandgirard, Bastien Morlet, Qingshuang Cai, Daniel Metzger, Delphine Duteil   +11 more
wiley   +1 more source

Moderate Aerobic Training Causes Muscle Wasting in a DMBA-Induced Sarcoma Rat Model. [PDF]

Int J Mol Sci
Correia RR, Veras ASC, Tavares MEA, Batista VRG, Cury SS, Oliveira JS, Fernandez GJ, Counts BR, Gaafer OU, Ota S, Frigo MM, Rodrigues RVEM, Sampaio LV, Chaves-Neto AH, Carvalho RF, Zimmers TA, Teixeira GR.   +16 more
europepmc   +1 more source

Organic Electrochemical Transistors for Neuromorphic Bioelectronics: Materials and Manufacturing Technologies

Advanced Science, EarlyView.
Organic electrochemical transistors bridge biological ionic signaling and neuromorphic computation through volumetric electrochemical gating. This review connects Organic mixed ionic–electronic conductor materials, device architectures, and manufacturing technologies to show how geometry, ion transport, and fabrication strategies program plasticity ...
Hyunjin Lee, Jihyang Park, Xinyi Wang, Yueqi Deng, Jiashu Ren, Tao Zhou   +5 more
wiley   +1 more source

High-fat diet and obesity each increase tumor cell proliferation and muscle wasting in experimental cancer cachexia. [PDF]

Am J Physiol Cell Physiol
Counts BR, Bonetto A, Chan HL, Au ED, Jiang Y, Couch ME, Guttridge DC, Ostrowski MC, Koniaris LG, Zimmers TA.   +9 more
europepmc   +1 more source

Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy

Advanced Science, EarlyView.
A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao, Yuechen Han, Jie Li, Peng Luo, Lin Qi, Zhiwei Xia, Xiaosong Li, Quan Cheng, Chenshen Huang, Wantao Wu, Hao Zhang   +10 more
wiley   +1 more source

Pathophysiological mechanisms and emerging therapeutic strategies for muscle wasting: an integrative review. [PDF]

Front Physiol
Huang J, Wen T, Wei H, Kang J, Lu J, Zhou T, Wen Y, Huang H.   +7 more
europepmc   +1 more source

Cross‐scale Material‐Structure Synergy for 2D Metamaterials: Toward Customizable Intelligent Electromagnetic Manipulation in Multiphysics Fields

Advanced Science, EarlyView.
Recent advances in metasurface‐enabled low‐observable technologies are reviewed from the perspective of cross‐scale material–structure synergy. Electromagnetic, thermal, optical, and acoustic stealth are highlighted together with dynamic tuning, programmable coding, data‐driven inverse design, artificial intelligence, multispectral compatibility, and ...
Shuhao Wang, Xing Yang, Liping Liu, Yang Peng, Yangyang Wang, Hualiang Lv   +5 more
wiley   +1 more source

The Role of Previous History of Muscle Wasting in Burn Outcomes-A Burn Care Quality Platform Study. [PDF]

Eur Burn J
Blears E, Godarzi J, Shania S, Kondisetti K, Caffrey J, Murton AJ.   +5 more
europepmc   +1 more source

Nuclear Translocation of PFKFB3 Promotes Disuse‐Induced Muscle Atrophy via Scaffolding Nedd4‐Mediated JunB Ubiquitination

Advanced Science, EarlyView.
Disuse‐induced muscle atrophy is driven by a non‐metabolic, nuclear function of the enzyme PFKFB3. Acting as a scaffold, PFKFB3 facilitates Nedd4‐mediated ubiquitination and degradation of the anti‐atrophy transcription factor JunB. Inhibiting this novel PFKFB3–Nedd4–JunB signaling axis stabilizes JunB and alleviates muscle wasting, revealing a highly ...
Mengjun Ma, Yinliang Liu, Wangchang Wu, Biao Yang, Jiahao Zhuang, Haoye Yu, Rujia Mi, Yixuan Lu, Wen Yang, Hanting Yi, Chenglong Yuan, Yinfeng Gu, Hongyu Li   +12 more
wiley   +1 more source

Adipose-Muscle Crosstalk in COPD Cachexia: Early Adipose Atrophy Drives Subsequent Muscle Wasting. [PDF]

J Cachexia Sarcopenia Muscle
Shimada T, Chubachi S, Nishikawa K, Arai T, Iizuka H, Otake S, Sakurai K, Hamamoto J, Sasaki M, Maetani T, Tanabe N, Masaki K, Kabata H, Miyata J, Yamada Y, Jinzaki M, Nakamura H, Asano K, Fukunaga K.   +18 more
europepmc   +1 more source