Results 1 to 10 of about 389,203 (187)

Muscle Weakness

Journal of Investigative Medicine High Impact Case Reports, 2017
Marked ligamentous hyperlaxity and muscle weakness/wasting associated with awkward gait are the main deficits confused with the diagnosis of myopathy.
Ali Al Kaissi MD, MSc, Sergey Ryabykh MD, Polina Ochirova MD, Vladimir Kenis MD, Jochen G. Hofstätter MD, Franz Grill MD, Rudolf Ganger MD, PhD, Susanne Gerit Kircher MD, MSc   +7 more
doaj   +3 more sources

Identifying Susceptibility Genes and Shared Genetic Architecture for Longevity and Muscle Weakness [PDF]

Journal of Cachexia, Sarcopenia and Muscle
Background Longevity and muscle strength are heritable traits, and age‐related muscle weakness is a major contributor to disability in older adults. However, the susceptibility genes and shared genetic mechanisms underlying lifespan and sarcopenia remain
Yilong Lin, Yun Zhang, Shengjie Lin, Songsong Wang, Zhiqiang Que, Yue Zhang, Jing She, Ruidan Zhao, Jiawei Chen, Anqi Qiu, Shinan Wu, Ruiqin Yang, Liyi Zhang, Qingmo Yang   +13 more
doaj   +2 more sources

The impact of lipid-rich nutrition on ketogenesis and muscle weakness in sepsis [PDF]

Intensive Care Medicine Experimental
Background Administration of ketone bodies attenuated the severity of sepsis-induced muscle weakness in preclinical studies. Whether lipid-rich emulsions may likewise mitigate such muscle weakness by stimulating the endogenous ketogenic capacity remains ...
Caroline Lauwers, Jan Gunst, Soraya El Dawy, Sarah Derde, Lies Pauwels, Inge Derese, Sarah Vander Perre, Greet Van den Berghe, Michael P. Casaer, Lies Langouche   +9 more
doaj   +2 more sources

Mitochondrial-targeted plastoquinone therapy prevents early onset muscle weakness that occurs before atrophy during ovarian cancer [PDF]

Molecular Metabolism
Objective: Muscle loss with cancer causes weakness, worsens quality of life, and predicts reduced overall survival rates. Recently, muscle weakness was identified during early-stage cancer before atrophy develops. This discovery indicates that mechanisms
Luca J. Delfinis, Shahrzad Khajehzadehshoushtar, Luke D. Flewwelling, Nathaniel J. Andrews, Madison C. Garibotti, Shivam Gandhi, Aditya N. Brahmbhatt, Brooke A. Morris, Bianca Garlisi, Sylvia Lauks, Caroline Aitken, Leslie Ogilvie, Stavroula Tsitkanou, Jeremy A. Simpson, Nicholas P. Greene, Arthur J. Cheng, Jim Petrik, Christopher G.R. Perry   +17 more
doaj   +2 more sources

Muscle weakness but also contractures contribute to the progressive gait pathology in children with Duchenne muscular dystrophy: a simulation study [PDF]

Journal of NeuroEngineering and Rehabilitation
Background Muscle weakness and contractures cause gait deficits in children with Duchenne muscular dystrophy (DMD) but their relative contributions are poorly understood and hence it is unclear whether contractures should be treated.
Ines Vandekerckhove, Lars D’Hondt, Dhruv Gupta, Bram Van Den Bosch, Marleen Van den Hauwe, Nathalie Goemans, Liesbeth De Waele, Anja Van Campenhout, Kaat Desloovere, Friedl De Groote   +9 more
doaj   +2 more sources

Sodium bicarbonate for the treatment of severe metabolic acidosis with moderate or severe acute kidney injury in the critically ill: protocol for a randomised clinical trial (BICARICU-2)

BMJ Open, 2023
Introduction When both severe metabolic acidemia (pH equal or less than 7.20; PaCO2 equal or less than 45 mm Hg and bicarbonate concentration equal or less than of 20 mmol/L) and moderate-to-severe acute kidney injury are observed, day 28 mortality is ...
Samir Jaber, Nicolas Molinari, Boris Jung, Helena Huguet   +3 more
doaj   +1 more source

Proximal muscle weakness [PDF]

Practical Neurology, 2019
A 38-year-old woman gave a 1-year history of difficulties climbing stairs and walking long distances, needing a wheelchair at times. More recently, she had also experienced weakness of her arms with difficulties doing her hair or lifting light weights. She reported shortness of breath on mild exertion and had lost 12 pounds in weight because of muscle ...
Gonzalez-Perez, Paloma, Torre, Matthew, Helgager, Jeffrey, Amato, Anthony A.   +3 more
openaire   +2 more sources

Muscle weakness, functional capacities and recovery for COVID-19 ICU survivors

BMC Anesthesiology, 2021
Background Few studies have evaluated muscle strength in COVID-19 ICU survivors. We aimed to report the incidence of limb and respiratory muscle weakness in COVID-19 ICU survivors.
Clément Medrinal, Guillaume Prieur, Tristan Bonnevie, Francis-Edouard Gravier, Denys Mayard, Emmanuelle Desmalles, Pauline Smondack, Bouchra Lamia, Yann Combret, Guillaume Fossat   +9 more
doaj   +1 more source

Muscle weakness in cerebral palsy

Acta Orthopaedica et Traumatologica Turcica, 2020
Over the last two decades, muscle weakness has been shown to be a major component of cerebral palsy (CP) pathology. Caused by multiple etiologies including variations in the muscle fiber type, pathologic motor unit function, co-contraction of agonists ...
Uri Givon
doaj   +1 more source

Causal influence of muscle weakness on cardiometabolic diseases and osteoporosis

Scientific Reports, 2023
The causal roles of muscle weakness in cardiometabolic diseases and osteoporosis remain elusive. This two-sample Mendelian randomization (MR) study aims to explore the causal roles of muscle weakness in the risk of cardiometabolic diseases and ...
Xiaoqing Mou, Bin He, Muzi Zhang, Yong Zhu, Yunsheng Ou, Xiaojun Chen   +5 more
doaj   +1 more source