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Background The hip abductor muscles, primarily the gluteus medius, play an important role in stabilizing the pelvis during gait. Gluteus medius weakness is associated with biomechanical changes and musculoskeletal disorders.
Rafael Ratti Fenato +2 more
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Post-COVID-19 Dermatomyositis: A Delayed Reaction That Evades Early Detection
Dermatomyositis (DM) is a rare autoimmune disease that causes symmetrical and predominantly proximal muscle weakness in the limbs and typical skin lesions. Its prevalence increased during the coronavirus disease-2019 (COVID-19) pandemic. Viral infections
Nur Ili Syazwani MD HADIS +3 more
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Tumor Growth Increases Neuroinflammation, Fatigue and Depressive-like Behavior Prior to Alterations in Muscle Function [PDF]
Cancer patients frequently suffer from fatigue, a complex syndrome associated with loss of muscle mass, weakness, and depressed mood. Cancer-related fatigue (CRF) can be present at the time of diagnosis, during treatment, and persists for years after ...
Bicer, Sabahattin +8 more
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Introduction: The objective of this study is to investigate the poor recordability characteristics of intraoperative neurophysiological monitoring (IONM) for metastatic spinal tumors, focusing on tumor status or preoperative muscle weakness.
Naoki Segi +26 more
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Assessment of Muscle Quantity, Quality and Function
Sarcopenia is a syndrome characterized by loss of skeletal muscle mass and strength that can increase the risk of physical disability, chronic conditions such as diabetes mellitus and cardiovascular diseases, and long-term mortality. Sarcopenia adversely
Bo Kyung Koo
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Nintedanib decreases muscle fibrosis and improves muscle function in a murine model of dystrophinopathy [PDF]
Duchenne muscle dystrophy (DMD) is a genetic disorder characterized by progressive skeletal muscle weakness. Dystrophin deficiency induces instability of the sarcolemma during muscle contraction that leads to muscle necrosis and replacement of muscle by ...
Díaz Manera, Jordi +6 more
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A young woman with muscle weakness [PDF]
Answers on p 284. A 28 year old woman presented with complaints of severe myalgias, muscle cramps and fatigue, of two weeks' duration. There was a history of pain and difficulty in rising from a squatting position and climbing up stairs. These symptoms, initially mild, had become exacerbated after the patient started cycling, …
N P, Singh, S, Anuradha, S K, Agarwal
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Recovery from acidosis is a robust trigger for loss of force in murine hypokalemic periodic paralysis. [PDF]
Periodic paralysis is an ion channelopathy of skeletal muscle in which recurrent episodes of weakness or paralysis are caused by sustained depolarization of the resting potential and thus reduction of fiber excitability.
Cannon, Stephen C +4 more
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Novel mutations expand the clinical spectrum of DYNC1H1-associated spinal muscular atrophy [PDF]
OBJECTIVE To expand the clinical phenotype of autosomal dominant congenital spinal muscular atrophy with lower extremity predominance (SMA-LED) due to mutations in the dynein, cytoplasmic 1, heavy chain 1 (DYNC1H1) gene.
Al-Lozi, Muhammad T +33 more
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Weakness is a common presentation of a wide variety of central and peripheral nervous system disorders. Weakness can be due to an organic CNS lesion or due to pseudoparalysis secondary to pain. Weakness due to brain lesion usually takes the distribution according to the site and extent of the lesion (e.g. hemiplegia, diplegia, quadriplegia).
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