Results 101 to 110 of about 1,349,150 (316)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Comparing the Force–Time Characteristics Between Countermovement and Assisted Countermovement Jump with Different Landing Strategies

Muscles
Researchers comparing countermovement (CMJ) and assisted countermovement (ACMJ) jumps reported conflicting findings on the landing impact force (LIF). This was likely due to differences in the landing strategies used.
Regine Y. S. Zhou, Lachlan P. James, Danny Lum   +2 more
doaj   +1 more source

Spatiotemporal symmetries in the disynaptic canal-neck projection [PDF]

, 2007
The vestibular system in almost all vertebrates, and in particular in humans, controls balance by employing a set of six semicircular canals, three in each inner ear, to detect angular accelerations of the head in three mutually orthogonal coordinate ...
Ian Stewart, LieJune Shiau, Martin Golubitsky, Shinoda Y., Wilson V. J.   +4 more
core   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

The Effect of Neck-Specific Exercise with or Without a Behavioral Approach in Chronic Whiplash-Associated Disorders: A Systematic Review and Meta-Analysis

Muscles
Chronic whiplash-associated disorders describe a cluster of symptoms that result from a sudden neck acceleration/deceleration movement, including pain, musculoskeletal and neurological signs, inducing functional disability.
Luís Correia, Paulo Carvalho, Luísa Amaral, Mário Esteves, Rui Vilarinho, Mariana Cervaens   +5 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Guidelines for Sport Compressive Garments Design: Finite Element Simulations Approach

Muscles
Purpose: Despite significant attention being paid to compression garments (CG) in the sports field, there remains ongoing debate regarding their actual effectiveness in enhancing athletic performance and expediting post-exercise recovery.
Alessandro Cudicio, Marta Cogliati, Gianluca Rizzi   +2 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Psoas Muscle Index Predicts Perioperative Mortality in Patients Undergoing LVAD Implantation

Muscles
Background: Sarcopenia is associated with adverse surgical outcomes across multiple specialties. The psoas muscle index (PMI), a radiologic marker of sarcopenia, may offer prognostic value in patients undergoing left ventricular assist device (LVAD ...
Steven Hopkins, Paulomi Gohel, Sakshi Gandhi, Moiz Nasir, William Stallings, Eman Hamad   +5 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source