Results 81 to 90 of about 624,554 (268)

Biopsychological Effects of Ashwagandha (Withania somnifera) in Athletes and Healthy Individuals: A Systematic Review

Muscles
Ergogenic supplements are becoming increasingly popular in the diet of trained individuals, due to their potential benefits. Ashwagandha (Withania somnifera) is one of the supplements that has recently grown in popularity.
João Francisco Ferreira, Ricardo Maia Ferreira, Filipe Maia, Luís Gonçalves Fernandes, César Leão, Nuno Pimenta   +5 more
doaj   +1 more source

Impaired training-induced angiogenesis process with loss of pericyte-endothelium interactions is associated with an abnormal capillary remodelling in the skeletal muscle of COPD patients

Respiratory Research, 2019
Chronic obstructive pulmonary disease (COPD) is associated with exercise intolerance and limits the functional gains in response to exercise training in patients compared to sedentary healthy subjects (SHS).
Léo Blervaque, Emilie Passerieux, Pascal Pomiès, Matthias Catteau, Nelly Héraud, Marine Blaquière, François Bughin, Bronia Ayoub, Nicolas Molinari, Jean-Paul Cristol, Antonia Perez-Martin, Jacques Mercier, Maurice Hayot, Fares Gouzi   +13 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Physiological and Physical Determinants of Flat-Water Kayaking

Muscles
The main research question of this review involved the identification of the various physiological and physical determinants of flat-water kayaking. A systematic search was conducted using three databases (PubMed, Google Scholar, and Microsoft Academic ...
Yi Shin Lee, Amelia Dingley, Danny Lum, Frankie Tan, John F. T. Fernandes   +4 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Sex Differences in Force, Velocity, and Power Percent Changes During Countermovement Jump Performance Following a Dynamic Warm-Up

Muscles
Background: The study examined sex differences in countermovement jump (CMJ) force plate metrics and neuromuscular responses to a standardized dynamic warm-up in physically active college students.
Gabriel J. Sanders, Maura Bennett, Roger O. Kollock, Corey A. Peacock   +3 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Muscle, Neuromuscular, and Cardiac Damage in Trail Running: A Systematic Review

Muscles
Background: Trail running (TR) is an endurance discipline characterized by prolonged exercise, irregular terrain, and marked elevation changes, which increase eccentric muscular load and may induce muscular, neuromuscular, and cardiac damage.
Isabel García-Valiente, Francisco Pradas, Miguel Ángel Ortega-Zayas, Carlos Castellar-Otín, Alejandro García-Giménez, Miguel Lecina   +5 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Tics, Tourette’s and Related Muscle Pain in Children: A Review

Muscles
Tourette Syndrome (TS) is a neurodevelopmental disorder depicted by the occurrence of tics and accompanying behavioral problems that commonly appear during childhood. Tics, both motor and vocal, may cause musculoskeletal pain.
Stuart Evans
doaj   +1 more source