Results 121 to 130 of about 3,357,773 (342)

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Sport-Related Injuries in Portuguese CrossFit® Practitioners and Their Characteristics

open access: yesMuscles
Background/Objectives: CrossFit® is one of the most popular yet controversial training regimens. Some groups extol the positive effects of its practice, while others argue that it is unsafe and that there is limited information. The aim of this study was
Ricardo Maia Ferreira   +5 more
doaj   +1 more source

Greater V˙O2peak is correlated with greater skeletal muscle deoxygenation amplitude and hemoglobin concentration within individual muscles during ramp-incremental cycle exercise. [PDF]

open access: yes, 2016
It is axiomatic that greater aerobic fitness (V˙O2peak) derives from enhanced perfusive and diffusive O2 conductances across active muscles. However, it remains unknown how these conductances might be reflected by regional differences in fractional O2 ...
Amano, Tatsuro   +7 more
core  

In vivo human gracilis whole-muscle passive stress–sarcomere strain relationship [PDF]

open access: bronze, 2021
Lomas S. Persad   +4 more
openalex   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

open access: yesFEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani   +7 more
wiley   +1 more source

Influence of History of Bronchiolitis on Health-Related Physical Fitness (Muscle Strength and Cardiorespiratory Fitness) in Children and Adolescents: A Cross-Sectional Study

open access: yesMuscles
A history of bronchiolitis may lead to changes in health-related physical fitness in children and adolescents. The aim of this study was to analyze the influence of history of bronchiolitis on health-related physical fitness components (muscle strength ...
Inês Silva de Carvalho   +2 more
doaj   +1 more source

Strengthening Your Hip Muscles: Some Exercises May Be Better Than Others [PDF]

open access: yes, 2014
Weak hip muscles lead to poor hip motion, and poor hip motion can cause knee, hip, and back pain. Strengthening hip muscles that control how hips move may reduce pain in these parts of the body.
Draper, Kaylee   +2 more
core   +1 more source

Smooth Muscle Cholesterol Enables BK β1 Subunit-Mediated Channel Inhibition and Subsequent Vasoconstriction Evoked by Alcohol [PDF]

open access: bronze, 2011
Anna N. Bukiya   +4 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Complete Upper Body Bar Enhances Strength Training During Bench Press

open access: yesMuscles
Barbell (BB) and dumbbell (DB) devices are commonly used during a bench press to develop the muscles of the chest, shoulders, and upper arms. Recently, a complete upper body bar (CUBB) was designed to train the muscles of the forearm by allowing for ...
He Wang   +6 more
doaj   +1 more source

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