Results 51 to 60 of about 3,255,580 (393)
Rejuvenation of the aged muscle stem cell population restores strength to injured aged muscles
The elderly often suffer from progressive muscle weakness and regenerative failure. We demonstrate that muscle regeneration is impaired with aging owing in part to a cell-autonomous functional decline in skeletal muscle stem cells (MuSCs).
B. Cosgrove+8 more
semanticscholar +1 more source
Autophagy in cancer and protein conformational disorders
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Age-Related Differences in Physical Fitness and Performance of an “Ability Test” among Firefighters
This study’s primary objective was to examine the differences in body composition, abdominal strength, absolute and relative power, handgrip strength, one repetition maximum for squat and bench press, and the maximum count of push-up and sit-up ...
Koulla Parpa, Marcos Michaelides
doaj +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
wiley +1 more source
Respiratory Sinus Arrhythmia (RSA) manifests as cyclic fluctuations in heart rate in synchrony with breathing. Gaining insights into the dynamics of RSA within the cardiac muscle functioning is crucial for comprehending its physiological and clinical ...
Erika Elizabeth Rodriguez-Torres+3 more
doaj +1 more source
Exercise-induced respiratory muscle fatigue: implications for performance [PDF]
It is commonly held that the respiratory system has ample capacity relative to the demand for maximal O-2 and CO2 transport in healthy humans exercising near sea level.
Polkey, MI, Romer, LM
core +1 more source
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source
Percussive therapy devices have been proven effective at reducing muscle inflammation, soreness, and tension and improving the range of motion before or after exercise.
Daniel R. Greene+2 more
doaj +1 more source
Musculoskeletal lower-limb robot driven by multifilament muscles
This paper presents a redundant musculoskeletal robot using thin McKibben muscles that is based on human anatomy. The purpose of this robot is to achieve motions and characteristics that are very similar to a human body.
Shunichi Kurumaya+3 more
semanticscholar +1 more source
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé+7 more
wiley +1 more source