Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang+4 more
wiley +1 more source
Prenatal carrier screening for spinal muscular atrophy among pregnant Thai women. [PDF]
Tangshewinsirikul C+9 more
europepmc +1 more source
The distal form of spinal muscular atrophy: an unusual case demonstrating the intermediate variety [PDF]
David Isenberg, Pauline A Kahn
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Human Nervous System‐Based Biohybrid Robot‐On‐A‐Chip with Sensing Function for Toxicity Screening
Human nervous system‐based biohybrid robot‐on‐a chip with eye function as sensing system in addition to brain/motor neuron/muscle functions is proposed. Upon light stimulation, the eye assembloid generates electrophysiological signals, which are transmitted through the cerebral organoid and motor neuron spheroid, inducing muscle movement.
Minkyu Shin+6 more
wiley +1 more source
Survey of feeding issues experienced by patients with spinal muscular atrophy type 2 in Japan. [PDF]
Uchio Y, Ikai T.
europepmc +1 more source
Hereditary distal muscular atrophy with vocal cord paralysis and sensorineural hearing loss: a dominant form of spinal muscular atrophy? [PDF]
Eugen Boltshauser+3 more
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This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie+8 more
wiley +1 more source
Cell adhesion molecule N-CAM is expressed by denervated myofibres in Werdnig-Hoffman and Kugelberg-Welander type spinal muscular atrophies. [PDF]
F S Walsh, S.E. Moore, B D Lake
openalex +1 more source
Significance of Dynamic Imaging in Diagnosis of Hirayama Disease: A Rare Case Report and Literature Review [PDF]
Acosta, Natasha, Kandukuri, Gautham
core +2 more sources