Results 261 to 270 of about 147,437 (336)

The Critical Role of Enhanced OXPHOS and Mitochondrial Hyperpolarization in Simulated Microgravity‐Induced Oocyte Maturation Arrest

Advanced Science, EarlyView.
Simulated microgravity induces distinct mitochondrial hyperactivation patterns‐elevated OXPHOS and MMP‐which accelerate meiosis without SAC failure but delays MTOC coalescence, leading to spindle defects and meiotic arrest. Prolonging M‐phase restores MTOC assembly and oocyte maturation.
Lei Ge, Yuqing Gao, Feifei Du, Chiyuan Ma, Tianxia Xiao, Yali Yang, Xiaohua Lei, Jian V. Zhang   +7 more
wiley   +1 more source

Spinal muscular atrophy is also a disorder of spermatogenesis. [PDF]

Orphanet J Rare Dis
Magot A, Reignier A, Binois O, Bedat-Millet AL, Davion JB, Debergé L, Ghorab K, Guyant L, Laheranne É, Laforet P, Lefeuvre C, Mallaret M, Michaud M, Omar C, Nadaj-Pakleza A, Nicolas G, Noury JB, Pegat A, Péré M, Salort-Campana E, Sole G, Spinazzi M, Tard C, Vuillerot C, Péréon Y.   +24 more
europepmc   +1 more source

Inhibition of AMPKα Pathway by Podocyte GOLM1 Exacerbates Diabetic Nephrology in Mice

Advanced Science, EarlyView.
Podocyte Golgi membrane protein 1 interacts with epidermal growth factor receptor to inhibit peroxisome proliferator activated receptor γ, and then inactivates adenosine monophosphate activated protein kinase α pathway, which facilitates diabetes‐related inflammation, oxidative damage, apoptosis, and renal dysfunction.
Peng Xu, Kaiqiang Li, Huasong Liu, Aibo Xu, Zhewei Zhang, Yimin Yang, Xiaobo Lai, Ke Hao, Kui Fang, Zeyu Lai, Xiping Ou, Yuqun Cai, Zhen Wang, Keda Lu, Wanli Jiang   +14 more
wiley   +1 more source

Healable Dielectric Elastomer Actuator With Premature Breakdown Warning Function for Information Transmission Encryption and Human‐Machine Interaction

Advanced Science, EarlyView.
An integral healable dielectric elastomer actuator (ISDEA) with a premature breakdown warning function is prepared based on the combination of electroluminescent dielectric elastomer and transparent compliant electrodes. Several ISDEAs are combined to construct soft anti‐counterfeiting labels and soft intelligent keyboards, expanding their potential ...
Yanze Liu, Shilin Luo, Jiawei Zhao, Lei Xu, Zhong‐Zhen Yu, Dan Yang   +5 more
wiley   +1 more source

Identifying Clinical Measures Related to Falls in Ambulatory Patients with Spinal and Bulbar Muscular Atrophy. [PDF]

Neurol Int
Shrader JA, Niemic AC, Jiménez-Silva R, Woolstenhulme JG, Joe GO, Jacobs U, Sansare A, Kokkinis A, Fischbeck K, Grunseich C, Zampieri C.   +10 more
europepmc   +1 more source

Muscular Atrophy of Bilateral Upper Extremities Associated with Cervical Spina Bifida

, 1991
Tatsuo Takahashi, Kazuyoshi Hattori, Shinichiro Tsugane, Kenji Imagawa, Akira Asai, Akio Kuwayama   +5 more
openalex   +2 more sources

Critical Design Strategy of Thermogalvanic Hydrogels for Low‐Grade Heat Harvesting

Advanced Science, EarlyView.
This review highlights thermogalvanic hydrogels for efficient low‐grade heat harvesting, with a focus on design strategies. Key aspects include recent advances, thermoelectrochemical conversion mechanisms, performance metrics, enhancement approaches, and current device applications.
Wentao Lin, Shukai Wu, Shuo Niu, Zhe Hu, Guangming Chen, Zhuoxin Liu, Yang Huang, Chao Fang   +7 more
wiley   +1 more source

Quantitative cervical cord MRI in spinal muscular atrophy: a sensitive imaging biomarker of disease evolution and treatment. [PDF]

J Neurol
Asteggiano C, Mazzocchi L, Farina L, Paoletti M, Barzaghi L, Caverzasi E, Parravicini S, Dainesi MI, Gardani A, Savini G, Bergsland N, Ballante E, Wheeler-Kingshott CAMG, Berardinelli A, Pichiecchio A.   +14 more
europepmc   +1 more source

Bioinspired Intelligent Soft Robotics: From Multidisciplinary Integration to Next‐Generation Intelligence

Advanced Science, EarlyView.
Soft robotics, featuring intrinsic compliance and biomimetic adaptability, emerges as transformative in next‐generation intelligent systems. This review outlines how advancements in four foundational domains—actuation, materials, manufacturing, and control—drive the evolution of bioinspired intelligent soft robotics, poised to redefine the boundaries ...
Xiaopeng Wang, Ruilai Wei, Zhongming Chen, Hao Pang, Haotian Li, Yang Yang, Qilin Hua, Guozhen Shen   +7 more
wiley   +1 more source