Results 111 to 120 of about 189,072 (321)

Critical illness polyneuromyopathy in septic patients: Is it possible to diagnose it in a bedside clinical examination?

open access: yesArquivos de Neuro-Psiquiatria
Objective: To determine the sensitivity and specificity of peripheral and respiratory muscle strength tests in diagnosing critical illness polyneuromyopathy (CIPNM), compared with an electrophysiological examination.
Débora Schmidt   +5 more
doaj   +1 more source

Misrepair mechanism in the development of atherosclerotic plaques [PDF]

open access: yesarXiv, 2015
Atherosclerosis is a disease characterized by the development of atherosclerotic plaques (APs) in arterial endothelium. The APs in part of an arterial wall are inhomogeneous on size and on distribution. In order to understand this in-homogeneity, the pathology of APs is analyzed by Misrepair mechanism, a mechanism proposed in our Misrepair-accumulation
arxiv  

Handling rescue therapy in myasthenia gravis clinical trials: why it matters and why you should care

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Myasthenia gravis (MG) clinical trials typically allow rescue therapy during follow‐up in the event of marked worsening of MG symptoms. Failure to appropriately address rescue therapy in defining treatment effects and planning statistical analyses may yield biased estimates, increase false positive rates, or decrease statistical power – all of
Justin M. Leach   +3 more
wiley   +1 more source

If it does not help, it might hurt: Pharmacodynamics of a second IVIg course in Guillain–Barré syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Objectives Intravenous immunoglobulin (IVIg) is an effective treatment for Guillain–Barré syndrome (GBS), but recovery varies between patients. This study aims to evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) of a single and a second IVIg dose (SID) in patients with GBS.
Sander J. van Tilburg   +7 more
wiley   +1 more source

Facts about Wildlife Diseases: Capture Myopathy in Farmed White-Tailed Deer

open access: yesEDIS
This publication discusses causes, clinical signs, and ways to reduce risk of capture myopathy in farmed white-tailed deer. Written by Juan M. Campos Krauer, and published by the Veterinary Medicine—Department of Large Animal Clinical Sciences, UF/IFAS ...
Juan Manuel Campos Krauer
doaj   +1 more source

Twelve‐month change in quantitative MRI calf muscle fat fraction in CMT1A predicts clinical change over 4 years

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Objective We measured clinical and quantitative MRI outcome measures in CMT1A to assess long‐term responsiveness, establish longitudinal validity and assess MRI as a bridging biomarker. Methods Twenty patients with CMT1A and 20 matched controls underwent MRI, myometry and clinical assessments up to four times over mean 4‐year follow‐up ...
Matthew R. B. Evans   +8 more
wiley   +1 more source

Editorial: Novel Mechanisms of Epileptogenesis and Its Inspired Pharmaceutical Treatments for Epilepsy

open access: yesFrontiers in Neurology, 2022
Antonella Riva   +3 more
doaj   +1 more source

Molecular diagnosis of muscular diseases in outpatient clinics: A Canadian perspective. [PDF]

open access: yesNeurol Genet, 2020
Thuriot F   +12 more
europepmc   +1 more source

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