Results 141 to 150 of about 182,997 (357)

Cases of Pseudo-Hypertrophic Paralysis and other Forms of Progressive Muscular Dystrophy [PDF]

, 1898
Jelliffe
openalex   +1 more source

Progress in Zinc Oxide‐Based Polymer Nanocomposites for Advancing Piezoelectric Energy Harvesting and Self‐Powered Devices

Macromolecular Materials and Engineering, EarlyView.
This review highlights synthesis routes, performance optimisation, and applications of fluoropolymers/ZnO nanocomposites, offering valuable insights into piezoelectricity optimisation of materials that empower next‐generation sensors, actuators, and sustainable energy solutions. ABSTRACT Piezoelectric materials convert mechanical energy into electrical
Daphne Mary John, Pratheep Kumar Annamalai, Alireza Hosseinmardi, Sreekanth Kaduvallil Mahadeva, Kothandaraman Ramanujam, Raghuram Chetty, Rajkumar Patel, Ramanujam Brahmadesam Thoopul Srinivasa Raghava, Ashok Kumar Nanjundan   +8 more
wiley   +1 more source

Patient engagement in clinical trial design for rare neuromuscular disorders: impact on the DELIVER and ACHIEVE clinical trials

Research Involvement and Engagement
Background Engaging individuals living with disease in drug development and regulatory processes leads to more thoughtful and sensitive trial designs, drives more informative and meaningful outcomes from clinical studies, and builds trust between the ...
Patricia Furlong, Ashish Dugar, Molly White   +2 more
doaj   +1 more source

Case of Pseudo-Hypertrophic Muscular Dystrophy Associated with Amentia [PDF]

, 1915
E. G. Fearnsides
openalex   +1 more source

Efficacy and Safety of IncobotulinumtoxinA for Treatment of Sialorrhea: A Multicenter, Phase 3 Study in Japan

Movement Disorders Clinical Practice, EarlyView.
This study demonstrated significant treatment efficacy and safety of incobotulinumtoxinA injection in Japanese patients with chronic sialorrhea caused by Parkinson's disease and other neurological conditions. Suppression of salivary secretion and improvement in drooling symptoms were also observed throughout 48 weeks.
Nobutaka Hattori, Yohei Mukai, Noriko Nishikawa, Kazuko Hasegawa, Masahiko Tomiyama, Yasuyoshi Kimura, Yoshio Tsuboi, Ryosuke Takahashi, Ryota Nakamura, Yuishin Izumi, Hirohisa Watanabe, Morinobu Seki, Kenji Sekiguchi, Shohei Tateishi, Yusaku Matsushita, Yusaku Nakamura   +15 more
wiley   +1 more source

Rapid Quantitative Assessment of Muscle Sodium Dynamics After Exercise Using 23Na‐MRI in Dysferlinopathy and Healthy Controls

Journal of Cachexia, Sarcopenia and Muscle
Background Dysferlin plays a key role in cell membrane repair; its absence or malfunction in patients with dysferlin‐deficient limb girdle muscular dystrophy leads to muscle fibre death.
Mary A. Neal, Carla F. Bolano‐Diaz, Mark Richardson, Jassi Michell‐Sodhi, Robert Muni‐Lofra, Meredith K. James, Kieren G. Hollingsworth, Heather Hilsden, Ian Wilson, Andrew M. Blamire, Volker Straub, Peter E. Thelwall, Jordi Diaz‐Manera   +12 more
doaj   +1 more source

Muscular Dystrophy in a Boy Aged 7 Years 9 Months [PDF]

, 1921
Paul B Roth
openalex   +1 more source

Spastic Ataxia Composite (SPAXCOM): A Scale to Evaluate the Progression of Subjects with Spasticity and Ataxia

Movement Disorders, EarlyView.
Abstract Background Current clinical scales that track disease progression are more tailored to spasticity or ataxia, with limited sensitivity to change. Objectives The aim was to develop a sensitive and valid scale specifically geared towards optimized sensitivity to change and adapted to patients presenting with both spasticity and ataxia.
Cécile Di Folco, Charlotte Dubec‐Fleury, Andreas Traschütz, Christoph Kessler, Selina Reich, Cynthia Gagnon, Isabelle Lessard, Xavier Rodrigue, Sirio Cocozza, Sara Satolli, Filippo M. Santorelli, Alexandra Durr, Anna Heinzmann, Bart P. van de Warrenburg, Ilse H.J. Willemse, A. Nazli Başak, Atay Vural, Bernard Brais, Stephan Klebe, Rita Horvath, PROSPAX Consortium, May Yung Tiet, Heather Biggs, Emma Harrison, Dagmar Timmann, Nicole Jeschonneck, Paulina Cunha, Hortense Hurmic, Lucie Pierron, Giulia Coarelli, Claire Ewenczyk, Ivana Ricca, Melissa Barghigiani, Nazan Akkaya, Özgür Öztop Çakmak, Rebecca Schüle, Matthis Synofzik, Sophie Tezenas du Montcel   +37 more
wiley   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

The Effect of Anti‐3‐Hydroxy‐3‐Methylglutaryl‐CoA Reductase (HMGCR) Human Autoantibodies on Muscle Regeneration in Mice

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Anti‐3‐hydroxy‐3‐methylglutaryl‐CoA reductase (HMGCR) autoantibodies (aAbs) are pathogenic in immune‐mediated necrotizing myopathy (IMNM), partly through complement activation. C5 inhibition did not restore muscle strength in mice or patients with overt IMNM, suggesting additional pathogenic mechanisms.
Sarah Julien, Honorine Tomasevic, Thara Jaworski, Rachid Zoubairi, Jeremie Martinet, Laurent Drouot, Olivier Boyer   +6 more
wiley   +1 more source