Results 51 to 60 of about 261,948 (310)

IRF5 suppresses metastasis through the regulation of tumor-derived extracellular vesicles and pre-metastatic niche formation

Scientific Reports
Metastasis is driven by extensive cooperation between a tumor and its microenvironment, resulting in the adaptation of molecular mechanisms that evade the immune system and enable pre-metastatic niche (PMN) formation.
Bailey K. Roberts, Dan Iris Li, Carter Somerville, Bharati Matta, Vaishali Jha, Adison Steinke, Zarina Brune, Lionel Blanc, Samuel Z. Soffer, Betsy J. Barnes   +9 more
doaj   +1 more source

Assessment and determinants of health care utilization among patients with musculoskeletal conditions undergoing outpatient rehabilitation in Germany [PDF]

, 2011
The overall objective of this doctoral thesis is to address some of the conditions necessary to routinely perform alongside economic evaluations of rehabilitation programs.
Sabariego, Carla
core  

Validation of the Pediatric Arthritis Ultrasound Scoring System for the Elbow, Wrist, and Finger Joints in Children With Juvenile Idiopathic Arthritis

Arthritis Care &Research, EarlyView.
Objective We aimed to validate the Pediatric Arthritis Ultrasound Scoring System (PAUSS) for upper extremity joints in children with juvenile idiopathic arthritis (JIA). Methods Children with JIA were evaluated for elbow, wrist, or finger arthritis by clinical examination (CE) and musculoskeletal ultrasound (MSUS) with images scored according to the ...
Patricia Vega‐Fernandez, Pinar Ozge Avar‐Aydin, Kelly Rogers, Daniel J. Lovell, Jennifer Huggins, Alexei Grom, Hermine I. Brunner, Grant S. Schulert, Sheila T. Angeles‐Han, Mekibib Altaye, Amy Cassedy, Arthur B. Meyers, Tracy V. Ting   +12 more
wiley   +1 more source

Evidence for C1q-mediated crosslinking of CD33/LAIR-1 inhibitory immunoreceptors and biological control of CD33/LAIR-1 expression

Scientific Reports, 2017
C1q collagen-like region (CLR) engaging and activating the LAIR-1 inhibitory immunoreceptor represents a non-complement mechanism for maintaining immune quiescence.
Myoungsun Son, Betty Diamond, Bruce T. Volpe, Cynthia B. Aranow, Meggan C. Mackay, Frances Santiago-Schwarz   +5 more
doaj   +1 more source

Musculoskeletal complications of haematological disease [PDF]

Rheumatology, 2015
Rheumatological manifestations complicate many benign and malignant blood disorders. Significant advances in haematology, with improved diagnostic techniques and newer musculoskeletal imaging, have occurred in the past two decades. This review focuses on the interrelationship between the major haematological diseases (haemochromatosis, haemophilia ...
Morais, SA, du Preez, HE, Akhtar, MR, Cross, S, Isenberg, DA   +4 more
openaire   +3 more sources

The effectiveness of therapeutic ultrasound for musculoskeletal conditions of the lower limb: a literature review

, 2010
Background: Ultrasound is suggested as one of the treatment options available for soft tissue musculoskeletal conditions of the lower limb and to this end, the objective was to review the literature and evaluate the effectiveness of therapeutic ...
Fletcher, Paul, Paul Fletcher, Curran, Mike, Pippa Shanks, Richard Thompson, Michael Curran, Shanks, Pippa, Thompson, Richard   +7 more
core   +1 more source

EULAR recommendations for cardiovascular risk management in rheumatic and musculoskeletal diseases, including systemic lupus erythematosus and antiphospholipid syndrome [PDF]

, 2022
OBJECTIVE: To develop recommendations for cardiovascular risk (CVR) management in gout, vasculitis, systemic sclerosis (SSc), myositis, mixed connective tissue disease (MCTD), Sjögren's syndrome (SS), systemic lupus erythematosus (SLE) and ...
Bruce, Ian N., Tektonidou, Maria G., Jacobsen, Søren, Mukhtyar, Chetan, Alan Tyndall, Boekel, Laura, Bruce, Ian N, Boumpas, Dimitrios T, Marchiori, Francesca, Tausche, Anne-Kathrin, Brodin, Nina, Svenungsson, Elisabet, Tausche, Anne Kathrin, Ward, Michael M., Gary J Macfarlane, Drosos, George C., Vedder, Daisy, Dimitrios T Boumpas, Nurmohamed, Michael T., Kerekes, Gyorgy, Michael T Nurmohamed, Boumpas, Dimitrios T., Macfarlane, Gary J., Anne-Kathrin Tausche, Fabiola Atzeni, Jacobsen, Soren, Manuel Ramos-Casals, Vokko van Halm, Atzeni, Fabiola, Michael M Ward, Naveed Sattar, Macfarlane, Gary, Laura Boekel, van Halm, Vokko, Tyndall, Alan, Sciascia, Savino, Sara Badreh, Gonzalez-Gay, Miguel Angel, Alexandre Voskuyl, Francesca Marchiori, Chetan Mukhtyar, Jacobsen, S. ren, Eline Houben, Nina Brodin, Ian N Bruce, Badreh, Sara, Macfarlane, Gary J, Voskuyl, Alexandre, Daisy Vedder, György Kerekes, Sattar, Naveed, Miguel Ángel González-Gay, Elisabet Svenungsson, Szekanecz, Zoltan, Søren Jacobsen, Savino Sciascia, Maria G Tektonidou, Houben, Eline, George C Drosos, Ramos-Casals, Manuel, Schreiber, Karen, Karen Schreiber, Zoltan Szekanecz   +62 more
core   +1 more source

Sex Differences in Medication Discontinuation in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or JAK inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we assessed ...
Rachael Stovall, Cinthia Blat, Eric Roberts, Jean W. Liew, Katherine Wysham, Namrata Singh, Janna Friedly, Lianne S. Gensler, Gabriela Schmajuk, Jinoos Yazdany   +9 more
wiley   +1 more source

Mechanoepigenetics in musculoskeletal disease

Osteoarthritis and Cartilage
This review explores the intricate interplay between genetic variants, mechanical forces, and the epigenetic landscape (defined as 'mechanoepigenetics'), particularly in the context of musculoskeletal (MSK) diseases such as osteoarthritis. Whilst our understanding of Mendelian monogenic disease has progressed with exome sequencing and the generation of
Coveney, Clarissa R., Capellini, Terence D.   +1 more
openaire   +3 more sources

Expert Consensus on Assessment for Rehabilitation and Treatment of Musculoskeletal Complications of Hemophilia in China

, 2022
Hemophilia is a group of hereditary hemorrhagic diseases. Hemorrhages mostly occur in musculoskeletal system and is the main cause for disability. Rehabilitation plays an important role in the comprehensive management in hemophilia.
Hemophilia Treatment Center Collaborative Network of China, China Alliance for Rare Diseases, Hemophilia Subcommittee   +1 more
core   +1 more source