Results 31 to 40 of about 2,495,332 (299)

Organisational downsizing and musculoskeletal problems in employees: a prospective study [PDF]

, 2001
Objectives: To study the association between organisational downsizing and subsequent musculoskeletal problems in employees and to determine the association with changes in psychosocial and behavioural risk factors.
Vahtera, J., Ferrie, J.E., Pentti, J., Hemingway, H., Kivimäki, M.   +4 more
core  

Genome-wide association studies and musculoskeletal diseases

, 2008
Bone and joint diseases are major causes of morbidity and mortality worldwide, and their prevalence is increasing as the average population age increases.
Brown, Matthew A., Danoy, P.
core   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

How to score the wrist joint by ultrasound: exploration of the most sensitive joint assessment during follow-up of early or established rheumatoid arthritis

Arthritis Research & Therapy
Background Wrist inflammation is common in patients with rheumatoid arthritis (RA), and thus there is room for debate on which joints to include in an ultrasound-based scoring of wrist synovitis in RA.
Yusuke Yoshida, Hilde Berner Hammer, Joseph Sexton, Lena Nordberg, Anna-Birgitte Aga, Lene Terslev, Siri Lillegraven, Espen A. Haarvardsholm   +7 more
doaj   +1 more source

Associations between synovitis and radiographic osteoarthritis progression in the first carpometacarpal and interphalangeal joints: results from the Nor-Hand study

RMD Open
Objectives To determine whether baseline synovitis detected by ultrasound or MRI predicts radiographic osteoarthritis (OA) progression in the first carpometacarpal (CMC1) and interphalangeal joints.Methods We included 201 participants with hand OA from ...
Ida K Haugen, Hilde Berner Hammer, Alexander Mathiessen, Marthe Gløersen, Øystein Maugesten, Lovisa Klingenberg   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Remote personalised exercise in axial spondyloarthritis: the SPARK trial – protocol for a 6-month randomised controlled trial

BMJ Open
Introduction Current international guidelines recommend exercise as a first-line treatment of axial spondyloarthritis (SpA). However, there is no consensus on the mode and volume required to effectively reduce disease activity.
Loreto Carmona, Siri Lillegraven, Hanne Dagfinrud, Silje Halvorsen Sveaas, Inger Jorid Berg, Eirik Klami Kristianslund, Nina Østerås, Sella Aarrestad Provan, Tanja Schjødt Jørgensen, Joe Sexton, Kristine Røren Nordén, Camilla Fongen, Birgitte Nellemann   +12 more
doaj   +1 more source

Occupational therapist and musculoskeletal diseases

, 2023
Occupational therapist' work related musculoskeletal ...
selen aydöner (14143329)
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

IRF5 suppresses metastasis through the regulation of tumor-derived extracellular vesicles and pre-metastatic niche formation

Scientific Reports
Metastasis is driven by extensive cooperation between a tumor and its microenvironment, resulting in the adaptation of molecular mechanisms that evade the immune system and enable pre-metastatic niche (PMN) formation.
Bailey K. Roberts, Dan Iris Li, Carter Somerville, Bharati Matta, Vaishali Jha, Adison Steinke, Zarina Brune, Lionel Blanc, Samuel Z. Soffer, Betsy J. Barnes   +9 more
doaj   +1 more source